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Ultrastructure of heat-deproteinated compact bone.
Biomaterials
May 1994
Institute of Human Anatomy, University of Bologna, Italy.
Heat-deproteinated bone (calcined bone) is a natural candidate for an osteoreproductive biomaterial. Ultrastructural investigation has pointed out an important aspect of the preparation technique. Treatment of bone at temperatures exceeding 500 degrees C causes complete disruption of the tissue architecture and the reorganization of the mineral phase into tightly packed, dense crystals.
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