Objective: To study the possible relationship between serum zinc levels and attention deficit hyperactivity disorder (ADHD) in Chinese children.
Methods: Following a systematic search for case-control studies on the serum zinc levels in Chinese children with ADHD published between 2000 and 2015, a Meta analysis was conducted using Stata 12.0 software.
Results: A total of 17 studies, including 2 177 children with ADHD and 2 900 normal children, were enrolled. The Meta analysis showed that serum zinc levels in children with ADHD were lower than normal children (SMD= -1.33; 95%CI: -2.22, -0.44; P=0.003). The sensitivity analysis indicated that the results were reliable. Eggerγs test did not find the existence of publication bias.
Conclusions: Serum zinc levels may be associated with susceptibility to ADHD in children.
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