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Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the spiramycin producer. | LitMetric

Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the spiramycin producer.

J Biotechnol

Université de Lorraine, Dynamique des Génomes et Adaptation Microbienne, UMR 1128, Vandœuvre-lès-Nancy F-54506, France; INRA, Dynamique des Génomes et Adaptation Microbienne, UMR 1128, Vandœuvre-lès-Nancy F-54506, France. Electronic address:

Published: November 2015

AI Article Synopsis

  • Streptomyces ambofaciens ATCC23877 is a soil bacterium used in industry to produce spiramycin, an antibacterial and anti-toxoplasmosis drug.
  • Its genome features an 8.3 Mbp linear chromosome and an 89 kb circular plasmid.
  • The complete genome sequence allows for research into genome evolution and the discovery of new secondary metabolites for potential medical use.

Article Abstract

Streptomyces ambofaciens ATCC23877 is a soil bacterium industrially exploited for the production of the macrolide spiramycin which is used in human medicine as an antibacterial and anti-toxoplasmosis chemical. Its genome consists of a 8.3 Mbp linear chromosome and a 89 kb circular plasmid. The complete genome sequence reported here will enable us to investigate Streptomyces genome evolution and to discover new secondary metabolites with potential applications notably in human medicine.

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Source
http://dx.doi.org/10.1016/j.jbiotec.2015.09.020DOI Listing

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