Background: Physical care after stroke is highly variable. The effects of therapeutic exercise on the impairments after stroke remain unclear.
Objective: To determine whether a structured, physiologically based exercise program for subacute stroke produces larger gains than those attributable to spontaneous recovery and usual care.
Methods: This randomized, controlled, single-blind pilot study was conducted in Yozgat, Turkey and enrolled 134 patients living in the community (mean age, 67 years; mean Barthel Index [BI] score, 67.4 ± 4.8) who consented to participate and were randomized from a screened sample of 765 patients. Of these, 72 patients completed the study. The intervention was a structured, progressive, physiologically based, nurse-supervised, in-home program of 24 1-h sessions over 12 weeks that targeted flexibility, strength, balance, endurance, and upper-limb function. The main outcome measures were postintervention activities of daily living (ADL) BI.
Results: The experimental group showed more improvement in ADL than the control group (BI: mean score change, 14). The BI scores in the experimental group were statistically significant (p < 0.001).
Conclusions: This study demonstrated that a pilot trial of a poststroke exercise program is feasible and is important with regard to accessibility of therapeutic exercise practice for patients at home. Improvements in the patients' neurological impairments and ADL implied the program was beneficial.
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http://dx.doi.org/10.3233/WOR-152156 | DOI Listing |
Neurol Int
December 2024
Division of Rehabilitation Medicine, Department of Medicine, National University Hospital, Singapore 119228, Singapore.
Background/objectives: Orthostatic hypotension (OH) is highly prevalent in hospitalized patients and can lead to major consequences. The prevalence of OH among patients with stroke has also been reported to be high in in-patient cohorts. However, no previous analysis has focused exclusively on patients with hemorrhagic stroke, a group that may have a different disease profile, including a greater need for blood pressure control and surgical intervention.
View Article and Find Full Text PDFAnn Neurol
December 2024
Department of Neurology, Jewish Hospital Berlin, Berlin, Germany.
Objective: Among patients with acute stroke, we aimed to identify those who will later develop central post-stroke pain (CPSP) versus those who will not (non-pain sensory stroke [NPSS]) by assessing potential differences in somatosensory profile patterns and evaluating their potential as predictors of CPSP.
Methods: In a prospective longitudinal study on 75 acute stroke patients with somatosensory symptoms, we performed quantitative somatosensory testing (QST) in the acute/subacute phase (within 10 days) and on follow-up visits for 12 months. Based on previous QST studies, we hypothesized that QST values of cold detection threshold (CDT) and dynamic mechanical allodynia (DMA) would differ between CPSP and NPSS patients before the onset of pain.
J Neuropsychol
December 2024
CNRS, LPNC, Université Grenoble Alpes, Université Savoie Mont Blanc, Grenoble, France.
Understanding the relative contribution of various factors influencing initial severity of aphasia and recovery after a stroke is essential for optimising neurorehabilitation programmes. We investigated how various significant sociodemographic, cognitive, clinical, stroke-related and rehabilitation-related factors modulate aphasia severity and language recovery following left-hemispheric stroke. Employing an innovative method, we conducted a retrospective analysis of 96 stroke participants to explore the combined impact of these factors.
View Article and Find Full Text PDFRegional neuron loss following stroke can result in remote brain changes due to diaschisis and secondary brain atrophy. Whole brain changes post-stroke can be captured by the predicted brain age difference (brain-PAD), a neuroimaging-derived biomarker of global brain health previously associated with poorer chronic stroke outcomes. We hypothesized that greater lesion damage would be longitudinally associated with worsening brain-PAD during subacute stroke, and conversely, that poorer baseline brain-PAD would be associated with enlarged lesion damage.
View Article and Find Full Text PDFJ Neuroeng Rehabil
December 2024
Key Laboratory of Biorheological Science and Technology of Ministry of Education, Chongqing University, Chongqing, 400044, P.R. China.
Background: Neural activation induced by upper extremity robot-assisted training (UE-RAT) helps characterize adaptive changes in the brains of poststroke patients, revealing differences in recovery potential among patients. However, it remains unclear whether these task-related neural activities can effectively predict rehabilitation outcomes. In this study, we utilized functional near-infrared spectroscopy (fNIRS) to measure participants' neural activity profiles during resting and UE-RAT tasks and developed models via machine learning to verify whether task-related functional brain responses can predict the recovery of upper limb motor function.
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