Contrast encephalopathy after coiling in the setting of obstructive sleep apnoea.

BMJ Case Rep

Department of Neurosurgery, UC Davis, Sacramento, California, USA.

Published: September 2015

Obstructive sleep apnoea (OSA) is increasingly recognised as a source of perioperative morbidity and mortality. We describe a patient with severe OSA who developed transient contrast encephalopathy after elective coiling of an anterior communicating artery aneurysm. Contrast extravasation led to cerebral oedema, seizures and delirium, which eventually completely resolved. OSA is known to be associated with a proinflammatory state that leads to hypertension, impaired endothelial repair capacity and endothelial dysfunction. Further studies are needed to clarify whether OSA increases the risk of endovascular procedures.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593243PMC
http://dx.doi.org/10.1136/bcr-2014-207503DOI Listing

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