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Human Infection with Ehrlichia muris-like Pathogen, United States, 2007-2013(1). | LitMetric

AI Article Synopsis

  • * Most affected individuals were older males (median age 63), with common symptoms including fever, malaise, and low platelet counts, all having a history of tick exposure.
  • * A significant portion of patients (23%) required hospitalization, but all recovered, and nearly all were treated with doxycycline, highlighting the importance of recognizing EML infections in tick-exposed individuals in the region.

Article Abstract

An Ehrlichia muris-like (EML) pathogen was detected among 4 patients in Minnesota and Wisconsin during 2009. We characterized additional cases clinically and epidemiologically. During 2004-2013, blood samples from 75,077 patients from all 50 United States were tested by PCR from the groEL gene for Ehrlichia spp. and Anaplasma phagocytophilum. During 2007-2013, samples from 69 (0.1%) patients were positive for the EML pathogen; patients were from 5 states: Indiana (1), Michigan (1), Minnesota (33), North Dakota (3), and Wisconsin (31). Most (64%) patients were male; median age was 63 (range 15-94) years; and all 69 patients reported likely tick exposure in Minnesota or Wisconsin. Fever, malaise, thrombocytopenia, and lymphopenia were the most common symptoms. Sixteen (23%) patients were hospitalized (median 4 days); all recovered, and 96% received doxycycline. Infection with the EML pathogen should be considered for persons reporting tick exposure in Minnesota or Wisconsin.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593436PMC
http://dx.doi.org/10.3201/eid2110.150143DOI Listing

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