Background: The breed-defining dorsal ridge in Rhodesian Ridgeback dogs is the result of a 133,000 base pair duplication on chromosome 18. Because this trait is dominant, heterozygous dogs cannot be discriminated from those with two copies of the Ridge allele.
Results: A quantitative PCR test was developed and dogs of known genotype were used as test subjects. In all cases, the correct genotype was determined experimentally.
Conclusions: This work provides a rapid and accurate methodology for determining dog genotype with respect to the Ridge allele.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579391 | PMC |
| http://dx.doi.org/10.1186/s40575-015-0013-x | DOI Listing |
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