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Molecular switch of the dendrite-to-spine transport of TDP-43/FMRP-bound neuronal mRNAs and its impairment in ASD.
Cell Mol Biol Lett
January 2025
PhD Program in Medical Neuroscience, Taipei Medical University, Taipei, Taiwan (R.O.C.).
Background: Regulation of messenger RNA (mRNA) transport and translation in neurons is essential for dendritic plasticity and learning/memory development. The trafficking of mRNAs along the hippocampal neuron dendrites remains translationally silent until they are selectively transported into the spines upon glutamate-induced receptor activation. However, the molecular mechanism(s) behind the spine entry of dendritic mRNAs under metabotropic glutamate receptor (mGluR)-mediated neuroactivation and long-term depression (LTD) as well as the fate of these mRNAs inside the spines are still elusive.
View Article and Find Full Text PDFSolvent-free upcycling of agricultural plastic waste using in situ self-assembly metal nanoparticles co-doped microporous carbocatalyst for advanced transportation fuels.
J Hazard Mater
January 2025
Engineering Laboratory for AgroBiomass Recycling & Valorizing, College of Engineering, China Agricultural University, Beijing 100083, China. Electronic address:
Plastic mulching film is ubiquitous in modern agriculture for its heat preservation and moisture retention functions. However, plastic mulching film waste accumulated on land results in microplastic pollution, posing potential hazards as these micro and nanoplastics can enter the food chain. Chemical upcycling of waste mulching film is an emerging strategy to realize sustainable development and circular economy.
View Article and Find Full Text PDFDataset on hydrogeochemical characteristics of spring and surface waters in the complex karst catchment area of Southern Dalmatia (Croatia) and Western Herzegovina (Bosnia and Herzegovina).
Data Brief
December 2024
University of Zagreb, Faculty of Mining, Geology and Petroleum Engineering, Pierottijeva 6, HR-10000 Zagreb, Croatia.
Large and complex karst catchments, like the one in Southern Dalmatia (Croatia) and Western Herzegovina (Bosnia and Herzegovina), are fragile environments requiring careful protection and sustainable water resources management. Understanding the processes that influence karst aquifer water chemistry is essential for the effective protection of water quality and quantity, ensuring sustainable resource availability and minimizing vulnerability to contamination. A hydrogeochemical dataset comprising over 30 groundwater (springs) and surface water samples, was collected in this cross-border catchment area from September 2013 to September 2020, accounting for seasonal variations.
View Article and Find Full Text PDFRISMEAU dataset: Pharmaceuticals and biocides concentrations in urban and agricultural sludge, amended soil and leachate and their environmental impacts.
Data Brief
December 2024
Universite Claude Bernard Lyon 1, CNRS, ISA, UMR5280, 5 rue de la Doua, F-69100 Villeurbanne, France.
The RISMEAU project ( - Risks related to residues of pharmaceuticals and biocides, and antimicrobial resistance of human and veterinary origin on the water resources of the 2083 km Arve catchment located in the French Alps) was implanted from 2018 to 2024 on the SIPIBEL observatory. It was devoted to the evaluation of (i) transfers of and processes related to pharmaceutical residues and biocides from both urban sludge and manure spread on fields as fertilisers, and (ii) the environmental impacts of land spreading, in particular the ecotoxicological risks and antimicrobial resistance dissemination. The methodology was based on the physico-chemical, ecotoxicological and antimicrobial resistance (AMR - assessed by molecular biology) characterisation of leachate and soil matrices samples, and focused on organic waste products application at locally representative agronomic rates.
View Article and Find Full Text PDFExploring the lunar water cycle.
Proc Natl Acad Sci U S A
December 2024
Technical University of Munich, School of Engineering and Design, Department of Aerospace and Geodesy, Ottobrunn 85521, Germany.
The presence of water on the Moon has been indicated by various remote-sensing observations and analyses of returned samples. Several missions are planned to conduct new in situ research on the lunar surface to directly observe and characterize lunar water. A comprehensive characterization of the present forms of water, their abundance, spatial distribution, temporal variation, and possible origin is required to understand the lunar water cycle and the relevance of individual source and sink mechanisms and transformations between the involved volatile species.
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