Purpose: The aim of this study was to evaluate the effect of dynamic elastomeric fabric orthoses (DEFOs) on postural control in children with cerebral palsy (CP).
Methods: Ten children with spastic diplegic CP and 10 children with typical development participated. Knee extension was measured using electrogoniometry. The standard deviation of excursion and phase plane portraits of velocity in the anteroposterior and mediolateral directions were calculated from force platform signals as center of pressure parameters with or without a DEFO.
Results: Maximum standing knee extension for children with CP improved after 6 weeks of wearing DEFOs (P < .05). Center of pressure parameters did not improve when comparing pre- to 6 weeks post-DEFO use (P < .05).
Conclusion: The DEFO can reduce the crouch position without any negative effect on postural stability in children with CP. However, postural control does not improve in a 6-week timeframe.
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http://dx.doi.org/10.1097/PEP.0000000000000171 | DOI Listing |
NPJ Digit Med
January 2025
Department of Neurology, University Hospital Schleswig-Holstein Campus Kiel, Kiel University, Kiel, Germany.
Fatigue is prevalent in immune-mediated inflammatory and neurodegenerative diseases, yet its assessment relies largely on patient-reported outcomes, which capture perception but not fluctuations over time. Wearable sensors, like inertial measurement units (IMUs), offer a way to monitor daily activities and evaluate functional capacity. This study investigates the relationship between sit-to-stand and stand-to-sit transitions and self-reported physical and mental fatigue in participants with Parkinson's, Huntington's, rheumatoid arthritis, systemic lupus erythematosus, primary Sjögren's syndrome and inflammatory bowel disease.
View Article and Find Full Text PDFSci Rep
January 2025
Division of Metabolic Disorders, CHOC Children's Hospital, Orange, CA, 92868, USA.
Neuronal ceroid lipofuscinosis type 2 (CLN2) is a rapidly progressive neurodegenerative disorder leading to premature mortality. Ambulatory CLN2 patients typically receive standard of care treatment through biweekly intracerebroventricular (ICV) enzyme replacement therapy (ERT) involving recombinant human tripeptidyl peptidase 1, known as cerliponase alfa (Brineura, Biomarin Pharmaceuticals). This study longitudinally assessed the impact of ICV cerliponase alfa ERT on gait, and postural control across a two-year span in two siblings diagnosed with atypical CLN2 disease.
View Article and Find Full Text PDFRev Med Chil
July 2024
Universidad de Chile, Santiago de Chile, Chile.
Unlabelled: Fibromyalgia is a syndrome of widespread chronic pain, associated with fatigue, sleep disorders, and a wide range of additional symptoms, among which balance disorders are a common complaint.
Aim: To determine a correlation between balance disorders and severity of fibromyalgia.
Methods: An observational cross-sectional study was conducted at the Pain Treatment Unit of the Clinical Hospital of the University of Chile.
Cureus
December 2024
Internal Medicine, Meharry Medical College, Nashville, USA.
Diabetic cardiac autonomic neuropathy (CAN) is caused by damage to the autonomic nerve fibers that innervate the heart and blood vessels, leading to abnormalities in heart rate control and vascular dynamics. CAN encompasses symptoms such as exercise intolerance, orthostatic hypotension, cardiac denervation syndrome, and nocturnal hypertension. Neurogenic orthostatic hypotension (nOH), resulting from severe diabetic CAN, can cause symptomatic orthostatic hypotension.
View Article and Find Full Text PDFJ Exerc Sci Fit
January 2025
Sports Medicine and Rehabilitation Center, Shanghai University of Sport, Shanghai, China.
Objective: This study aimed to evaluate bilateral sensorimotor function in patients with unilateral CAI. Furthermore, sensory reweighting ability and vestibular modulation were assessed.
Methods: Twenty individuals with unilateral CAI and twenty healthy controls participated in this study.
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