Diatom-Specific Oligosaccharide and Polysaccharide Structures Help to Unravel Biosynthetic Capabilities in Diatoms.

Mar Drugs

Laboratoire Glyco-MEV EA 4358, Université de Rouen, Normandie Université, Institut de Recherche et d'Innovation Biomédicale (IRIB), Végétale Agronomie Sol Innovation (VASI), Normandie Université, Faculté des Sciences et Techniques, 76821 Mont-Saint-Aignan, France.

Published: September 2015

Diatoms are marine organisms that represent one of the most important sources of biomass in the ocean, accounting for about 40% of marine primary production, and in the biosphere, contributing up to 20% of global CO₂ fixation. There has been a recent surge in developing the use of diatoms as a source of bioactive compounds in the food and cosmetic industries. In addition, the potential of diatoms such as Phaeodactylum tricornutum as cell factories for the production of biopharmaceuticals is currently under evaluation. These biotechnological applications require a comprehensive understanding of the sugar biosynthesis pathways that operate in diatoms. Here, we review diatom glycan and polysaccharide structures, thus revealing their sugar biosynthesis capabilities.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584364PMC
http://dx.doi.org/10.3390/md13095993DOI Listing

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