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Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources.
Foods
December 2024
Department of Cardio-Thoracic Pathology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Polyunsaturated fatty acids (PUFAs) are vital dietary elements that play a significant role in human nutrition. They are highly regarded for their positive contributions to overall health and well-being. Beyond the fact that they provide a substantial supply of energy to the body (a role that saturated fats can also perform), these unsaturated fatty acids and, especially, the essential ones are involved in cell membrane structure, blood pressure regulation, and coagulation; participate in the proper functioning of the immune system and assimilation of fat-soluble vitamins; influence the synthesis of pro- and anti-inflammatory substances; and protect the cardiovascular system.
View Article and Find Full Text PDFComparative Analysis of Mechanistic and Correlative Models for Global and Bhutan-Specific Suitability of Parthenium Weed and Vulnerability of Agriculture in Bhutan.
Plants (Basel)
December 2024
School of Agriculture and Food Sustainability, The University of Queensland, Gatton, QLD 4343, Australia.
Parthenium weed ( L.) is one of the most noxious and fast-spreading invasive alien species, posing a major threat to ecosystems, agriculture, and public health worldwide. Mechanistic and correlative species distribution models are commonly employed to determine the potential habitat suitability of parthenium weed.
View Article and Find Full Text PDFConformation and binding of 12 Microcystin (MC) congeners to PPP1 using molecular dynamics simulations: a potential approach in support of an improved MC risk assessment.
Chem Biol Interact
January 2025
Department of Informatics and Information Science, University of Konstanz, Germany; Faculty of Information Technology, Monash University, Australia. Electronic address:
Microcystins (MCs) occur frequently during cyanobacterial blooms worldwide, representing a group of currently about 300 known MC congeners, which are structurally highly similar. Human exposure to MCs via contaminated water, food or dietary supplements can lead to severe intoxications with ensuing high morbidity and in some cases mortality. Currently, one MC congener (MC-LR) is almost exclusively considered for risk assessment (RA) by the WHO.
View Article and Find Full Text PDFWheat2035: Integrating Pan-omics and Advanced Biotechnology for Future Wheat Design.
Mol Plant
January 2025
Frontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), and Beijing Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing 100193, China. Electronic address:
Wheat (Triticum aestivum L.) production is vital for global food security, providing energy and protein to millions of people worldwide. Recent advancements in wheat research have led to significant increases in production, fueled by technological and scientific innovation.
View Article and Find Full Text PDFGlucose Metabolism Reprogramming of Immune Cells in the Microenvironment of Pancreatic and Hepatobiliary Cancers.
J Gastroenterol Hepatol
January 2025
The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China.
Background And Aim: Pancreatic and hepatobiliary cancers are increasing in prevalence and contribute significantly to cancer-related mortality worldwide. Emerging therapeutic approaches, particularly immunotherapy, are gaining attention for their potential to harness the patient's immune system to combat these tumors. Understanding the role of immune cells in the tumor microenvironment (TME) and their metabolic reprogramming is key to developing more effective treatment strategies.
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