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Effects of denosumab and zoledronic acid on postmenopausal osteoporosis, bone density, and fat-free mass.
Arch Osteoporos
January 2025
Division of Endocrinology & Metabolism, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Unlabelled: This study compared denosumab and zoledronic acid for treating osteoporosis in drug-naïve postmenopausal Korean women. Over 3 years, both drugs significantly increased bone mineral density. However, denosumab also improved fat-free mass, suggesting it may be a better initial treatment for osteoporosis with low muscle mass, assuming all other conditions remain constant.
View Article and Find Full Text PDFIn vitro evaluation of dye penetration and dentin microhardness after laser irradiation using photon-induced photoacoustic streaming and shock wave enhanced emission photoacoustic streaming tips compared to ultrasonic activation.
Lasers Med Sci
January 2025
Conservative Dentistry Department and Tissue Engineering Laboratories, Faculty of Dentistry, Alexandria University, Alexandria, Alexandria, Egypt.
The purpose of this study was to compare the penetration of methylene blue (MB) dye after laser irradiation using PIPS (photon-induced photoacoustic streaming) and SWEEPS (shockwave enhanced emission photoacoustic streaming) methods compared to Passive ultrasonic irrigation (PUI) and to study their effect on dentin microhardness. A total of 44 single-rooted human teeth which were extracted for orthodontic or periodontal reasons were used. The teeth were decapitated to standardize roots to 12 mm in length.
View Article and Find Full Text PDFSelf-rated health differences between exclusive e-cigarette users and exclusive cigarette smokers: evidence from the 2017-2019 Scottish Health Survey.
Intern Emerg Med
January 2025
Nuffield Department of Population Health, University of Oxford, Oxford, UK.
The comparative health implications of e-cigarette use versus traditional cigarette smoking remain a critical focus in public health research. This cross-sectional study examined differences in self-rated general health between exclusive e-cigarette users and exclusive cigarette smokers, using data from the 2017-2019 Scottish Health Survey. A total of 2484 adults (aged 16 and above) were included and categorized as exclusive e-cigarette users (n = 565) or exclusive cigarette smokers (n = 1919).
View Article and Find Full Text PDFCharacteristics of Sciatic Scoliosis in Lumbar Disc Herniation and Comparative Radiographic Outcomes After Treatment With Full-Endoscopic Interlaminar Discectomy.
Asian J Endosc Surg
January 2025
Research Unit, Institute of Orthopedics, Lerdsin Hospital, Department of Orthopaedic Surgery, College of Medicine, Rangsit University, Bangkok, Thailand.
Study Design: Retrospective cohort study.
Background: Sciatic scoliosis is attributed to non-structural scoliosis resulting from the irritation of spinal nerve roots. Although limited research has addressed the specific characteristics of sciatic scoliotic curve patterns, there is a lack of reported data on the pre- and post-radiographic outcomes of patients with sciatic scoliosis caused by lumbar disc herniation who have undergone full-endoscopic interlaminar discectomy (FEID).
Aims: Large-scale, real-world data on early initiation of sacubitril/valsartan in patients newly diagnosed (de novo) with HF with reduced ejection fraction (HFrEF) are limited. We examined the effectiveness of sacubitril/valsartan versus angiotensin-converting enzyme inhibitor (ACEi)/angiotensin receptor blocker (ARB) on all-cause and cause-specific hospitalizations among patients with de novo HFrEF from the Optum® dataset in the United States.
Methods: This retrospective cohort study included adult patients with de novo HFrEF (diagnosed ≤30 days) with left ventricular ejection fraction (LVEF) ≤40% who were first prescribed with sacubitril/valsartan or ACEi/ARB from 1 January 2016 to 31 March 2020.
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