HIV is more prevalent in the prison population compared to the general population. Prison inmates are at an increased risk of blood-borne infections. Considerable stigma has been documented amongst inmates with HIV infection. In collaboration with the schools, healthcare facilities, prison authorities and inmate Irish Red Cross groups in Wheatfield, Cloverhill and Mountjoy prisons in Dublin, Ireland, the Department of Genito Urinary Medicine and Infectious Diseases at St James' Hospital in Dublin developed a campaign for raising awareness of HIV, educating inmates about HIV and tackling HIV stigma. Following this campaign, large-scale point-of-care testing for HIV was offered over a short period. In total, 741 inmates were screened for HIV. One inmate tested positive for HIV. We experienced a large number of invalid test results, requiring formal laboratory serum testing, and a small number of false positive results. Large-scale point-of-care testing in the Irish prison setting is acceptable and achievable.
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http://dx.doi.org/10.1177/0956462415601340 | DOI Listing |
Vet Sci
January 2025
Sydney School of Veterinary Science, Faculty of Science, The University of Sydney, Sydney, NSW 2006, Australia.
The primary aim of this study was to determine the accuracy of saliva as a proxy for blood in cats using Anigen Rapid FIV point-of-care (PoC) kits and as an easy collection technique applicable for all veterinary clinics and shelters. A secondary aim was to report FIV prevalence in various Australian states/territories and key cat risk factors associated with FIV infection. In total, 382 cats were recruited from patients presenting to private, shelter and teaching hospital veterinary clinics in Australia.
View Article and Find Full Text PDFBiosensors (Basel)
January 2025
Department of Bioengineering, Faculty of Engineering, Ege University, 35040 Izmir, Türkiye.
Drug abuse is a major public problem in the workplace, traffic, and forensic issues, which requires a standardized test device to monitor on-site drug use. For field testing, the most important requirements are portability, sensitivity, non-invasiveness, and quick results. Motivated by this problem, a point of care (POC) test based on lateral flow assay (LFA) was developed for the detection of cocaine (COC) and methamphetamine (MET) in saliva which has been selected as the matrix for this study due to its rapid and non-invasive collection process.
View Article and Find Full Text PDFBiosensors (Basel)
January 2025
Department of Computer and Information Sciences, University of Houston-Victoria, Victoria, TX 77904, USA.
Lateral flow assay has been extensively used for at-home testing and point-of-care diagnostics in rural areas. Despite its advantages as convenient and low-cost testing, it suffers from poor quantification capacity where only yes/no or positive/negative diagnostics are achieved. In this study, machine learning and deep learning models were developed to quantify the analyte load from smartphone-captured images of the lateral flow assay test.
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January 2025
Department of Biomedical Laboratory Science, Daegu Health College, Chang-ui Building, 15 Yeongsong-ro, Buk-gu, Daegu 41453, Republic of Korea.
Point-of-care (POC) use is one of the essential goals of biosensing platforms. Because the increasing demand for testing cannot be met by a centralized laboratory-based strategy, rapid and frequent testing at the right time and place will be key to increasing health and safety. To date, however, there are still difficulties in developing a simple and affordable, as well as sensitive and effective, platform that enables POC use.
View Article and Find Full Text PDFCells
January 2025
Department of Cardiovascular Sciences, University of Leicester, Leicester LE1 7RH, UK.
Osteopontin (OPN) is a sialylated phosphoprotein highly expressed in atherosclerosis and upregulated in settings of both acute and chronic inflammation. It is hypothesised that plasma levels of OPN may correlate with the presence of coronary artery disease, "CAD". This offers potential as a point-of-care testing biomarker for early diagnosis, disease monitoring, and prognosis.
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