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Impact of cerebral collateral recycle status on clinical outcomes in elderly patients with endovascular stroke treatment.
J Neuroradiol
December 2024
Department of Neurology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, PR China. Electronic address:
Article Synopsis
- Elderly patients are significantly at risk for acute ischemic stroke caused by large vessel occlusion, which often leads to serious disabilities despite treatment. This study investigates the impact of cerebral collateral recycle (CCR) status on outcomes for these patients undergoing endovascular treatment (EVT).
- In a retrospective study involving 338 elderly patients, those with moderate to favorable CCR showed much higher rates of functional independence (63.3% and 31.1% respectively) compared to those with poor CCR (10.2%). The odds of achieving better outcomes were significantly higher for patients in the moderate and favorable CCR groups.
- The research concludes that the status of cerebral collaterals is a strong predictor of functional outcomes for elderly AIS
The cortical vein opacification score (COVES) is independently associated with DSA ASITN collateral score.
AJNR Am J Neuroradiol
November 2024
From the Department of Radiology and Radiological Sciences (D.A.L., A.B.B., H.S., R.W., J.M., V.Y.), and Department of Neurology (A.E.H.), Johns Hopkins University, Baltimore, MD, USA; Department of Neuroradiology (D.A.L., S.A., M.K., A.T.R.), and Department of Biostatistics (S.W.), West Virginia University, Morgantown, WV, USA; Cooper Medical School of Rowan University (M.K.), Camden, NJ, USA; Department of Neurology (J.J.H., G.W.A.), Stanford University, Stanford, CA, USA; Department of Radiology (A.A.D.), Harvard Medical School, Boston, MA, USA; Department of Radiology, Neuroendovascular Division (T.D.F.), University Medical Center Münster, Germany; Department of Neuroradiology (M.W.), MD Anderson Medical Center, Houston, TX, USA; Department of Radiology (K.N.), University of California San Francisco, CA, USA.
: Pretreatment CTA-based Cortical Vein Opacification Score (COVES) has been shown to predict good functional outcomes at 90 days in patients with acute ischemic stroke secondary to large vessel occlusion (AIS-LVO). This is thought to be related to its ability to measure collateral status (CS). However, its association with the reference standard test, the DSA-based American Society of Interventional and Therapeutic Neuroradiology (ASITN) collateral score, has yet to be established.
View Article and Find Full Text PDFA rare case of infiltrative optic neuropathy caused by vitreoretinal lymphoma with hyperreflective deposits in the intraretinal and subretinal pigment epithelial layers prior to the disease onset.
BMC Ophthalmol
November 2024
Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan.
Background: To describe a rare case of infiltrative optic neuropathy (ION) caused by vitreoretinal lymphoma (VRL) with hyperreflective deposits in the intraretinal and subretinal pigment epithelial (RPE) layers before the disease onset.
Case Presentation: An 87-year-old Japanese female, previously treated for unexplained uveitis in the right eye, was referred for further evaluation. Despite the absence of intraocular inflammation or vitreous opacification (VO), yellowish-white deposits were noted in the macula, and OCT revealed hyperreflective deposits in the intraretinal and sub-RPE layers.
Rapid posterior capsular opacification in two patients treated for negative dysphotopsias.
BMC Ophthalmol
November 2024
Ophthalmology, Bascom Palmer Eye Institute University of Miami Miller School of Medicine, Miami, Florida, USA.
Background: Negative dysphotopsias (ND) are visual aberrations associated with in-the-bag optic intraocular lens (IOL) placement, causing arc-shaped or linear shadows. Reverse optic capture (ROC) is employed to prevent ND, yet it poses the risk of posterior capsular opacification (PCO) which usually develops within 2-5 years post-surgery due to the lens epithelial cells (LECs) proliferation and migration onto the posterior capsule. This can lead to a cloudy or hazy appearance in the visual field.
View Article and Find Full Text PDFTacrolimus-Associated Maculopathy in a Patient Following Kidney Transplantation.
Cureus
September 2024
Ophthalmology, Cairo University, Cairo, EGY.
Article Synopsis
- * A male patient experienced acute vision loss 19 days after starting tacrolimus, coinciding with increased drug levels, leading to a diagnosis of ischemic maculopathy.
- * After switching to cyclosporin, the patient's vision improved, and retinal damage was resolved, highlighting the serious risks of tacrolimus toxicity.
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