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Evaluation of tumor microvasculature with 3D ultrasound localization microscopy based on 2D matrix array.
Eur Radiol
August 2024
Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Objective: Evaluation of tumor microvascular morphology is of great significance in tumor diagnosis, therapeutic effect prediction, and surgical planning. Recently, two-dimensional ultrasound localization microscopy (2DULM) has demonstrated its superiority in the field of microvascular imaging. However, it suffers from planar dependence and is unintuitive.
View Article and Find Full Text PDFIn vivo ocular microvasculature imaging in rabbits with 3D ultrasound localization microscopy.
Ultrasonics
August 2023
Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; National Innovation Center for Advanced Medical Devices, Shenzhen 518126, China. Electronic address:
Morphological and hemodynamic changes in the ocular vasculature are important signs of various ocular diseases. The evaluation of the ocular microvasculature with high resolution is valuable in comprehensive diagnoses. However, it is difficult for current optical imaging techniques to visualize the posterior segment and retrobulbar microvasculature due to the limited penetration depth of light, particularly when the refractive medium is opaque.
View Article and Find Full Text PDFRobust principal component analysis in optical micro-angiography.
Quant Imaging Med Surg
December 2017
Department of Bioengineering, University of Washington, Seattle, WA, USA.
Background: Recent development of optical micro-angiography (OMAG) utilizes principal component analysis (PCA), where linear-regression filter is employed to separate static and blood flow signals within optical coherence tomography (OCT). While PCA is relatively simple and computationally efficient, the technique is sensitive to and easily skewed by outliers. In this paper, robust PCA (RPCA) is thus introduced to tackle this issue in traditional PCA.
View Article and Find Full Text PDFIn vivo micro-angiography by means of speckle-variance optical coherence tomography (SV-OCT) is able to detect microscopic vascular changes in naevus to melanoma transition.
J Eur Acad Dermatol Venereol
October 2016
Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.
Association between endothelial function and micro-vascular remodeling measured by synchrotron radiation pulmonary micro-angiography in pulmonary arterial hypertension.
Gen Thorac Cardiovasc Surg
October 2016
Department of Cardiovascular Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8577, Japan.
Objectives: Pulmonary arterial hypertension (PAH) is a progressive disease which causes increased vascular resistance. In this study, our purpose was to quantify the micro-vascular remodeling in monocrotaline-induced PAH rats using synchrotron radiation pulmonary micro-angiography (SRPA), a method we have previously established in an in vivo rat model. To determine the relationship between endothelial function and vascular remodeling, the local expression of endothelin-1 (ET-1), endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) was evaluated using immunohistochemical staining.
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