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Rotavirus-Associated Myocarditis in an Immunocompetent Adult: A Case Report.
Cureus
December 2024
Internal Medicine, Weiss Memorial Hospital, Chicago, USA.
A previously healthy, 28-year-old man presented with a two-day history of diarrhea and chest pain, suggestive of infectious myocarditis. Initial workup revealed elevated troponin-I levels and diffuse ST-segment elevations on electrocardiogram (ECG). Transthoracic echocardiography showed a reduced left ventricular ejection fraction (40-45%), posteroinferior wall akinesis, and a small pericardial effusion.
View Article and Find Full Text PDFRelationship between myocardial fibrosis and left bundle branch block. Does it exist?
Cardiovasc Pathol
December 2024
Chazov National Medical Research Center of Cardiology, 121552, Academician Chazov str., 15a, Moscow, Russian Federation.
Aim: to assess the relation of focal and diffuse left ventricular (LV) fibrosis to left bundle branch block (LBBB).
Materials And Methods: 60 patients with dilated cardiomyopathy and LBBB (DCM-LBBB), 50 DCM-nonLBBB patients, 15 patients with LBBB and structurally normal heart (idiopathic LBBB) and 10 healthy volunteers (HV) underwent cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE). LGE LV images were post-proceed for core scar (CS) and gray zone (GZ) calculation.
Heart failure of very rare aetiology-haemochromatosis Type 3: a case report.
Eur Heart J Case Rep
December 2024
Faculty of Medicine, Lithuanian University of Health Sciences, A. Mickevičiaus Str. 9, 44307 Kaunas, Lithuania.
Background: Haemochromatosis is a pathological condition characterized by the accumulation of iron in parenchymal organs, leading to toxic damage and dysfunction. Cardiac haemochromatosis represents one of the rare causes of severe heart failure (HF) that can be potentially prevented with targeted treatment.
Case Summary: We present the case of a 41-year-old female who was hospitalized for decompensated HF.
Emerging role of circulating piRNAs in the diagnosis of heart transplant rejection.
J Heart Lung Transplant
December 2024
Clinical and Translational Research in Cardiology Unit, Health Research Institute Hospital La Fe (IISLaFe), Valencia, Spain; Center for Biomedical Research Network on Cardiovascular Diseases, Madrid, Spain. Electronic address:
Background: Liquid biopsy offers a potential alternative to decrease or eliminate endomyocardial biopsy for diagnosing allograft rejection. p-element-induced wimpy testis-interacting RNAs (piRNAs) are novel and promising disease biomarkers for their intrinsic characteristics such as stability in body fluids; however, their role in allograft rejection remains unexplored.
Methods: A training set based on small RNA sequencing technology was performed to identify piRNAs in endomyocardial tissue (n = 8) and serum samples (n = 40) from patients following heart transplantation.
Endomyocardial biopsy in the diagnosis of cardiac sarcoidosis.
Eur J Heart Fail
December 2024
Heart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Aims: We set out to assess the utility of endomyocardial biopsy (EMB) in cardiac sarcoidosis (CS). Historically, EMB sensitivity in CS is only ≤25%, but comprehensive analyses of its current diagnostic performance are not available.
Methods And Results: The data of 260 consecutive patients with CS (mean age 49 years, 60% female) meeting the Heart Rhythm Society diagnostic criteria were analysed retrospectively.
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