Background: Osteochondromas are benign bony tumours, with only 1 to 4% being located in the spine. It occurs more frequently in the cervical spine, with C2 being the vertebra most affected. The neurological presentation is slow due to the growth characteristics of the tumour. Computed axial tomography is the reference method for diagnosis. Surgical management is indicated for patients with neurological impairment or pain.
Clinical Case: The first case presents a 21-year-old male with osteochondroma located in the spinous processes of L2, L3 and L4. The second case is a 20-year-old female with multiple osteochondromatosis with tumours at the right lateral mass of C1, with extension to C2 and tumours on the spinous processes of C5 and C7. Both patients presented with painful symptoms, which were resolved after surgical resection of the tumours.
Conclusions: The rarity of these conditions, relevance of a clinical-radiographic diagnosis, and considerations required for surgical treatment are discussed here.
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http://dx.doi.org/10.1016/j.circir.2015.07.002 | DOI Listing |
Achondroplasia, the most prevalent short-stature disorder, is caused by missense variants overactivating the fibroblast growth factor receptor 3 (FGFR3). As current surgical and pharmaceutical treatments only partially improve some disease features, we sought to explore a genetic approach. We show that an enhancer located 29 kb upstream of mouse Fgfr3 (-29E) is sufficient to confer a transgenic mouse reporter with a domain of expression in cartilage matching that of Fgfr3.
View Article and Find Full Text PDFJ Spine Surg
December 2024
Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, China.
Background: Vertebral body tethering (VBT) has shown improvements in coronal and sagittal plane correction in adolescent idiopathic scoliosis (AIS) patients, but axial correction over time remains unexplored. Three-dimensional (3D) spine reconstruction was used to analyse correctional changes in all spinal planes post VBT surgery.
Case Description: AIS subjects who underwent thoracic VBT surgery with a minimum 2-year follow-up were assessed.
J Spine Surg
December 2024
Department of Orthopedic Surgery, Toyama Prefectural Central Hospital, Toyama City, Japan.
Background: There is no consensus on the association between final local kyphosis and residual back pain (RBP) after traumatic vertebral fracture. The aim of this study was to investigate whether there is an association between the final local kyphosis angle and RBP in patients with traumatic vertebral fractures at the thoracolumbar junction who underwent single posterior surgery with percutaneous pedicle screws and implant removal after fracture healing. A second goal was to determine the optimal cut-off value for the final local kyphosis angle with and without RBP.
View Article and Find Full Text PDFSkeletal Radiol
January 2025
Department of Radiology, Fukui Prefectural Hospital, 2-8-1 Yotsui, Fukui City, 910-8526, Japan.
Objectives: Paravertebral crystal deposition disease, characterized by the deposition of crystals around the vertebral bodies leading to acute inflammation and pain, is a condition that remains largely unrecognized. This study aims to elucidate the prevalence, clinical features, and CT findings associated with this disease.
Methods: We retrospectively analyzed 14,839 consecutive patients who underwent chest and/or abdominal CT (September 2017 to September 2024) owing to chest, abdominal, or back pain.
J Bone Joint Surg Am
November 2024
Department of Neurosurgery, Bokwang Hospital, Daegu, Republic of Korea.
Background: Oblique lumbar interbody fusion (OLIF) results in less tissue damage than in other surgeries, but immediate postoperative pain occurs. Notably, facet joint widening occurs in the vertebral body after OLIF. We hypothesized that the application of a facet joint block to the area of widening would relieve facet joint pain.
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