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Blood-based epigenome-wide association study and prediction of alcohol consumption.
Clin Epigenetics
January 2025
Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Alcohol consumption is an important risk factor for multiple diseases. It is typically assessed via self-report, which is open to measurement error through recall bias. Instead, molecular data such as blood-based DNA methylation (DNAm) could be used to derive a more objective measure of alcohol consumption by incorporating information from cytosine-phosphate-guanine (CpG) sites known to be linked to the trait.
View Article and Find Full Text PDFResearch on the application effect of self-transcendence nursing model in patients with gestational diabetes mellitus: a randomised controlled trial.
BMC Pregnancy Childbirth
January 2025
Editorial Board of Jiangsu Medical Journal, the First Affiliated Hospital With Nanjing Medical University, Nanjing, 210029, China.
Background: Gestational diabetes mellitus is hyperglycemia in special populations (pregnant women), however gestational diabetes mellitus (GDM) not only affects maternal health, but also has profound effects on offspring health. The prevalence of gestational diabetes in my country is gradually increasing.
Objective: To study the application effect of self-transcendence nursing model in GDM patients.
Safety outcome trials in four mainline medical journals 30 years apart: a narrative review and the need for the transparency of informed consents.
Trials
January 2025
Internal Medicine (Rheumatology), Academic Hospital, Istanbul, Turkey.
Background: It was our impression that safety outcome trials were getting more frequent, raising ethical issues mainly related to patient autonomy. We and others had also proposed this autonomy would be best served if wording of the informed consents would be in the public domain.
Methods: Initially two observers and an arbiter tabulated the main aims of randomized controlled trials (RCTs) published in 1990-1991 vs.
Mechanism of microscopic behind the influence of stress loading on gas adsorption by coal.
Sci Rep
January 2025
College of Environment and Bioengineering, Henan University of Engineering, Zhengzhou, 451191, China.
This study aims to explore the mechanism behind the influence of stress on gas adsorption by coal during deep mining and improve the accuracy of gas disaster prevention and control. To achieve this aim, thermodynamic analysis was conducted on the process of gas adsorption by loaded coal, and modified thermodynamic model proposed by previous scholars. It is found that stress plays an important role in gas adsorption by coal.
View Article and Find Full Text PDFThe effect of avatar identity on spontaneous perspective-taking in patients with schizophrenia.
Schizophrenia (Heidelb)
January 2025
School of Psychology, Northwest Normal University, Lanzhou, China.
Controversy exists regarding whether the spontaneity of altercentric intrusion is impaired in patients with schizophrenia during implicit visual perspective-taking tasks. This study explored the characteristics of spontaneous visual perspective-taking in patients with schizophrenia and the effect of an avatar identity on their perspective-taking. We recruited 65 patients with schizophrenia and 65 healthy participants to complete 4 visual perspective-taking experiments for uncued other-avatar and self-avatar tasks and cued other-avatar and self-avatar tasks.
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