Challenging responsive behaviours, such as aggression, wandering and social inappropriateness, exhibited by persons with neurological, mental health or developmental disorders are of increasing concern across Canada. These behaviours can cause distress or catastrophic outcomes for the person, others in care, caregivers and healthcare providers, and result in extensive resource utilization. The objective of this paper is to discuss the role and impact of a unique, grassroots provincial initiative aimed at networking among healthcare providers, decision-makers and caregivers across government ministries and service-provider agencies. This collaboration provides a model for informing service provision and policy development across multiple stakeholders.
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http://dx.doi.org/10.12927/hcq.2015.24302 | DOI Listing |
Transl Oncol
January 2025
Johns Hopkins Greenberg Bladder Cancer Institute, Brady Urological Institute, Johns Hopkins University, Baltimore, MD, USA. Electronic address:
Bladder cancer (BLCA) genomic profiling has identified molecular subtypes with distinct clinical characteristics and variable sensitivities to frontline therapy. BLCAs can be categorized into luminal or basal subtypes based on their gene expression. We comprehensively characterized nine human BLCA cell lines (UC3, UC6, UC9, UC13, UC14, T24, SCaBER, RT4V6 and RT112) into molecular subtypes using orthotopic xenograft models.
View Article and Find Full Text PDFJ Speech Lang Hear Res
January 2025
Department of Communication Sciences and Disorders, Bowling Green State University, OH.
Purpose: The current project aimed to examine the effects of two experimental cognitive-linguistic paradigms, the Stroop task and a primed Stroop task, on speech kinematics and perioral muscle activation.
Method: Acoustic, kinematic, and surface electromyographic data were collected from the verbal responses of 30 young adult healthy control participants in choice response, classic Stroop, and primed Stroop tasks. The classic and primed Stroop tasks included congruent and incongruent trials.
J Trauma Nurs
January 2025
Author Affiliations: Penn Medicine, Department of Advanced Practice & Trauma Surgical Critical Care (Dr Saucier), Biostatistics, Hearing, & Speech, Ingram Cancer Center, Vanderbilt University School of Medicine (Dr Dietrich), School of Nursing, Vanderbilt University (Drs Maxwell and Minnick), Nashville, Tennessee; David E. Longnecker Associate Professor of Anesthesiology and Critical Care (Dr Lane-Fall), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; and Surgical Service Line (Dr Messing), Inova Health System, Falls Church, Virginia.
Background: Patient transitions in critical care require coordination across provider roles and rely on the quality of providers' actions to ensure safety. Studying the behavior of providers who transition patients in critical care may guide future interventions that ultimately improve patient safety in this setting.
Objective: To establish the feasibility of using the Theory of Planned Behavior in a trauma environment and to describe provider behavior elements during trauma patient transfers (de-escalations) to non-critical care units.
CBE Life Sci Educ
March 2025
Department of Psychology, Northeastern University, Boston, MA, 02115.
Previous research has shown that students employ intuitive thinking when understanding scientific concepts. Three types of intuitive thinking-essentialist, teleological, and anthropic thinking-are used in biology learning and can lead to misconceptions. However, it is unknown how commonly these types of intuitive thinking, or cognitive construals, are used spontaneously in students' explanations across biological concepts and whether this usage is related to endorsement of construal-consistent misconceptions.
View Article and Find Full Text PDFPLoS Comput Biol
January 2025
Department of Mathematics and Statistics, Middlebury College, Middlebury, Vermont, United States of America.
Chronic pain is a wide-spread condition that is debilitating and expensive to manage, costing the United States alone around $600 billion in 2010. In a common symptom of chronic pain called allodynia, non-painful stimuli produce painful responses with highly variable presentations across individuals. While the specific mechanisms remain unclear, allodynia is hypothesized to be caused by the dysregulation of excitatory-inhibitory (E-I) balance in pain-processing neural circuitry in the dorsal horn of the spinal cord.
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