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Pelvic floor muscle training for the prevention and management of low anterior resection syndrome in patients with rectal cancer: An evidence-based summary.
Asia Pac J Oncol Nurs
December 2025
School of Nursing, Hangzhou Normal University, Hangzhou, China.
Objective: This study aims to summarize the best available evidence on the effectiveness of pelvic floor muscle training (PFMT) in preventing and managing low anterior resection syndrome (LARS) among patients with rectal cancer, with the goal of enhancing quality of care.
Methods: A systematic search was conducted across databases, including BMJ Best Practice, UpToDate, WHO, GIN, UK NICE, NGC, SIGN, RNAO, NCCN, JBI Library, Cochrane Library, CINAHL, Web of Science, Embase, OVID, PubMed, Chinese Wanfang, CNKI, SinoMed, and VIP, covering publications from inception through June 30, 2024. We targeted clinical decisions, guidelines, evidence summaries, expert consensus statements, systematic reviews, and randomized controlled trials related to PFMT for LARS in patients with rectal cancer.
NCCN guideline concordance in colon and rectal cancer patients within a comprehensive health system.
Am J Surg
November 2024
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA; Surgical Outcomes and Quality Improvement Center, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA; Regenstrief Institute, Inc., Indianapolis, IN, USA. Electronic address:
Background: The National Comprehensive Cancer Care Network (NCCN) provides recommendations for patients with colorectal cancer. Concordance with evidence-based guidelines improves outcomes. Our objectives were to 1) examine rates of guideline non-concordance in a large vertically integrated health system; 2) examine factors associated with non-concordant care, and 3) identify geographical patterns of non-concordant care.
View Article and Find Full Text PDFCorrelations between 14-gene RNA-level assay and clinical and molecular features in resectable non-squamous non-small cell lung cancer: a cross-sectional study.
Transl Lung Cancer Res
November 2024
Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. Accurate risk stratification is essential for optimizing treatment strategies. A 14-gene RNA-level assay of lung cancer, which involves quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis of formalin-fixed paraffin-embedded (FFPE) tissue samples, offers a promising approach.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the use of generative AI, like ChatGPT, to support precision oncology, specifically in non-small cell lung cancer (NSCLC), addressing challenges in biomarker testing and treatment recommendations.
- Researchers assessed the accuracy of different ChatGPT versions in generating NSCLC treatment recommendations against established guidelines, utilizing a Generative AI Performance Score (G-PS) to quantify their effectiveness.
- Results showed that GPT-4 significantly outperformed GPT-3.5, demonstrating better accuracy and fewer inaccuracies (hallucinations), indicating advancements in AI's role in personalized cancer treatment.
Associations of Financial Toxicity with Employment Concerns and Cancer-Related Distress: A Cross-Sectional Survey among Korean Working-Age Cancer Survivors.
Cancer Res Treat
December 2024
Department of Preventive Medicine, Korea University College of Medicine, Seoul, Korea.
Purpose: Although South Korea's health insurance has a co-payment-decreasing policy for cancer survivors, information on the extent of financial toxicity and its related factors is limited. We assessed the level of financial toxicity and the association of high levels of financial toxicity with employment concerns after diagnosis and cancer-related distress in working-age cancer survivors.
Materials And Methods: A cross-sectional study was conducted.
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