Aim: To study the relationship between mild head trauma (MHT) and arterial ischemic stroke (AIS) in children.
Material And Methods: We examined 81 patients with AIS, aged from 1 month to 15 years. The sample was stratified into two groups: patients with AIS caused by MHT (main group) and patients without MHT (comparison group).
Results And Conclusion: Based on the results of clinical and instrumental studies, we identified the relationship between AIS and MHT. The main group was characterized by the following features: moderate severity in the acute period, stabilization within 7 days, isolated subcortical localization of ischemic lesion, no MRI-signs of steno-occlusive cerebral arteriopathy and a trend towards the risk of recurrent strokes.
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http://dx.doi.org/10.17116/jnevro20151155228-34 | DOI Listing |
Sci Adv
January 2025
Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
We applied an MRI technique diffusion tensor imaging along the perivascular space (DTI-ALPS) for assessing glymphatic system (GS) in a genome-wide association study (GWAS) and phenome-wide association study (PheWAS) of 40,486 European individuals. Exploratory analysis revealed 17 genetic loci significantly associating with the regional DTI-ALPS index. We found 58 genes, including and , which prioritized in the DTI-ALPS index subtypes and associated with neurodegenerative diseases.
View Article and Find Full Text PDFMicroglia M1 polarization plays important role in the development of ischemic stroke (IS). This study explored the role of transcription factor 7 like 2 (TCF7L2) in regulating microglia M1 polarization during IS. TTC staining was used to determine the cerebral infarction, and Nissl staining was applied to examine neuronal injury.
View Article and Find Full Text PDFJACC Case Rep
December 2024
Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
We present a case of a patient with a left atrial myxoma who presented with an ischemic stroke. Her cardiac myxoma had an irregular contour and was highly mobile, both features that have been associated with a greater risk of thromboembolism. She was treated with prompt surgical resection.
View Article and Find Full Text PDFAm J Transl Res
December 2024
Department of Neurology, Zhejiang Sian International Hospital Jiaxing 314031, Zhejiang, China.
Objective: To evaluate the effectiveness of combination therapy based on motion feedback training in patients recovering from ischemic stroke.
Methods: A retrospective analysis was conducted on 205 patients in the recovery phase of ischemic stroke admitted between June 2022 and June 2023. Patients were divided into two groups: the conventional treatment group (n=101), receiving standard care, and the combination therapy group (n=104), receiving additional motion feedback training for 30 days.
Cureus
December 2024
General Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, IND.
Objectives The study aimed at estimating the triglyceride glucose (TyG) index in patients with ischemic stroke, exploring the correlation between the TyG index and the prognosis of ischemic stroke, and studying the clinical outcome in patients with acute ischemic stroke (AIS) in association with the TyG index. Methods An observational study was conducted on 105 patients with a history of AIS presenting within 24 hours. The TyG index was estimated, and the clinical outcome was studied.
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