Arteriovenous dysplasia is rather uncommon disease, quite often leading to severe complications even in young age. Involvement of the osseous apparatus into the pathological process is frequently associated with the problem of amputation of the affected limb. Therefore, salvage of the extremity while removing arteriovenous shunt and trophic impairments is an extremely important clinical task. In the presented herein clinical case report, a female patient with arteriovenous angiodysplasia of the lower limb with the tibial bone involved into the pathological process underwent repeated stagewise embolisations, failing however to achieve complete liquidation of the arteriovenous reflux. In this connection, after removal of angiomatous tissues, requiring also excochleation of the damaged portions of the bone, in order to reinforce the axis of the tibial bone the intramedullary canal of the latter was filled with polymethylmethacrylate (PMMA). Expansion of the spectrum of auxiliary methods, besides the most frequently performed in such patients embolisations of afferent arteries and removal of angiomatous tissues would make it possible to increase radical nature of interventions with salvage of the supporting function of limbs.
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J Med Cases
January 2025
Gastroenterology and Hepatology, St. Joseph's University Medical Center, Paterson, NJ, USA.
Heyde syndrome is a triad of aortic stenosis (AS), gastrointestinal (GI) bleeding from angiodysplasia, and acquired von Willebrand disease (vWD). It is hypothesized that stenotic aortic valves cleave von Willebrand factor (vWF) multimers, predisposing patients to bleeding from GI angiodysplasias. This hypothesis is supported by the observation that aortic valve replacement often leads to the resolution of GI bleeding.
View Article and Find Full Text PDFJ Funct Morphol Kinesiol
November 2024
Faculty of Psychology, eCampus University, 22060 Novedrate, Italy.
: This case study involved a 24-year-old male with an arteriovenous malformation localized in the long head of the right biceps femoris muscle, with an anterior cruciate ligament injury. The aim was to assess the effects of a five-week kinesiological protocol, which included global postural re-education and strengthening exercises focused on knee stabilization. The effectiveness of the therapeutic intervention was evaluated using Gait Analysis, clinical examination, and the SF-36 questionnaire to assess the patient's quality of life.
View Article and Find Full Text PDFMedicine (Baltimore)
October 2024
Department of Gastroenterology, The First Hospital of Jilin University, Changchun, China.
J Stroke Cerebrovasc Dis
June 2024
A.R.G Argentine Rendu Study Group, Hereditary Hemorrhagic Telangiectasia Unit and Internal Medicine Department, Hospital Italiano de Buenos Aires, Argentina.
J Med Genet
July 2024
Service de Génétique et Centre de référence pour la maladie de Rendu-Osler, Femme-Mère-Enfants Hospital, Hospices Civils de Lyon, Bron, France
Background: Both hereditary haemorrhagic telangiectasia (HHT) and juvenile polyposis syndrome (JPS) are known to be caused by pathogenic variants, with overlapping symptoms for both disorders in some patients. Additional connective tissue disorders have also been reported. Here, we describe carriers of variants followed in an HHT reference centre to further delineate the phenotype.
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