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Effectiveness of General Practitioners' Involvement in Adult Vaccination Practices: A Systematic Review and Meta-Analysis of International Evidence.
Vaccines (Basel)
December 2024
Unit of Hygiene and Medical Statistics, Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.
Background: General practitioners (GPs) and primary care units collaborate with Prevention Departments (PDs) to improve immunization by participating in vaccination campaigns, sharing tools, and implementing educational programs to raise patient awareness. This review aimed to identify effective strategies for involving GPs in PD vaccination practices.
Methods: A systematic review following PRISMA guidelines was conducted on MEDLINE, TripDatabase, ClinicalTrials, CINAHL, and Cochrane up to January 2024 to identify full-text studies in English evaluating the effectiveness of GP involvement.
Vaccination Promotion Strategies in the Elderly: Systematic Review and Meta-Analysis.
Vaccines (Basel)
December 2024
ESS, Polytechnic of Porto, Rua Dr. António Bernardino de Almeida 400, 4200-072 Porto, Portugal.
The World Health Organization estimates that currently available vaccines prevent 2 to 3 million deaths worldwide each year. Preventing infectious diseases is an important public health priority to ensure healthy ageing and improve quality of life. This study's aim is to identify the best strategies to increase vaccination coverage in the elderly.
View Article and Find Full Text PDFThe Role of Pharmacometrics in Advancing the Therapies for Autoimmune Diseases.
Pharmaceutics
December 2024
Department of Pharmacokinetics and Physical Pharmacy, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland.
Autoimmune diseases (AIDs) are a group of disorders in which the immune system attacks the body's own tissues, leading to chronic inflammation and organ damage. These diseases are difficult to treat due to variability in drug PK among individuals, patient responses to treatment, and the side effects of long-term immunosuppressive therapies. In recent years, pharmacometrics has emerged as a critical tool in drug discovery and development (DDD) and precision medicine.
View Article and Find Full Text PDFEnergy, Aromatic, and Medicinal Plants' Potential and Prospects for the Remediation of Potentially Toxic Element-Contaminated Agricultural Soils: A Critical Meta-Analysis.
Toxics
December 2024
Soil Science Laboratory, School of Agriculture, Faculty of Agriculture, Forestry and Natural Environment, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece.
A critical meta-analysis of the past decade's investigations was carried out with the aim of assessing the use of plant-based techniques for soil remediation. Potentially toxic element (PTE) contaminated soils were selected since these contaminants are considered hazardous and have long-term effects. Furthermore, energy, aromatic, and medicinal plants were studied as their high-value products seem to be affected by PTEs' existence.
View Article and Find Full Text PDFThe Efficacy and Safety of Roxadustat for Anemia in Hemodialysis Patients with Chronic Kidney Disease: A Meta-Analysis of Randomized Controlled Trials.
Toxics
November 2024
Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Renal Research Institution of Beijing University of Chinese Medicine, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China.
Background: Patients undergoing hemodialysis (HD) for chronic kidney disease (CKD) often encounter anemia. Roxadustat has not only undergone phase II-III clinical trials in patients suffering from CKD and undergoing HD; a number of post-marketing clinical studies have been conducted using the drug. This article was to assess the effectiveness and safety of roxadustat in managing anemia among patients with CKD undergoing HD.
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