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Retrospective evaluation of "Rods and Rings" pattern detected in the anti-nuclear antibody (ANA) indirect immunofluorescence (IIF) test.
Front Immunol
June 2024
Department of Medical Microbiology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
Introduction: Anti-rods and rings (anti-RR) antibodies have recently been described as a cytoplasmic pattern in IIF-based screening of autoantibodies on HEp-2 cells and ICAP has named it as AC-23. It is most frequently related to drug-induced antibody generation. This study aimed to investigate the clinical significance of AC-23 positivity and its relevance to the diagnosis and/or follow-up of the associated diseases and/or drug use.
View Article and Find Full Text PDFThe value of anti-rods and rings antibodies in Chinese population of Dalian City: A retrospective study.
Scand J Immunol
June 2023
Department of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
The study aimed to investigate the clinical significance of anti-rods and rings (anti-RR) antibodies in antinuclear antibodies (ANAs) test samples retrospectively. The laboratory data and clinical details of patients with positive anti-RR antibodies were collected and analysed between December 2017 and May 2022 in the First Affiliated Hospital of Dalian Medical University. A total of 72 665 patients were tested for ANAs.
View Article and Find Full Text PDFThe clinical value of indirect immunofluorescence for screening anti-rods and rings antibodies: A retrospective study of two centers in China.
Front Immunol
October 2022
Department of Rheumatology and Clinical Immunology, Chinese Academy of Medical Sciences & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China.
Objective: To investigate the distribution and clinical significance of the rods and rings (RR) pattern in various diseases.
Methods: A total of 169,891 patients in Peking Union Medical College Hospital (PUMCH) and 29,458 patients in Inner Mongolia People's Hospital (IMPH) from January 2018 to December 2020 were included, and the results of ANA (antinuclear antibodies) and special antibodies were analyzed retrospectively.
Results: The positive rates of ANA and RR patterns were 34.
Anti-rods/rings autoantibodies in a patient with pancreatic injury.
Autoimmun Rev
January 2022
Department of Psychiatry and Behavioral Sciences, Tokyo Medical and Dental University Graduate School, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8510, Japan. Electronic address:
The aim of this study was to retrospectively investigate the clinical significance of anti-rods and rings (anti-RR) antibodies in nonhepatitis virus infection patients from Southwest China.Anti-RR antibodies were determined by indirect immunofluorescence assay in a group of 19,935 individuals with antinuclear antibodies test from January 2017 to December 2019. The laboratory and clinical data were collected.
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