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Intraoperative radiotherapy boost as part of breast-conservation therapy for breast cancer: a single-institution retrospective analysis.
Strahlenther Onkol
September 2021
Department of Radiation Oncology, University Hospital of Freiburg, Robert-Koch-Straße 3, 79106, Freiburg, Germany.
Article Synopsis
- The study looked at how safe and effective a type of radiation therapy called intraoperative radiotherapy (IORT) is for breast cancer patients who had surgery to save their breasts.
- It reviewed data from 2015 to 2019 and involved 214 patients who got IORT along with regular breast radiation afterward.
- Results showed that most patients did well, with only a small number experiencing serious side effects or cancer recurrence in the treated area.
Prognostic validation and treatment decision making of the 8 edition of the American Joint Committee on Cancer pathological staging system for elderly women with early-stage breast cancer.
Aging (Albany NY)
July 2020
Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, People's Republic of China.
Purpose: To determine the prognostication and treatment decision making of the American Joint Committee on Cancer (AJCC) 8 pathological staging system in elderly women (aged ≥65 years) with T1-2N0M0 breast cancer (BC).
Results: We included 67699 patients, and patients were restaged into stage IA (84.9%), IB (8.
Cosmetic Outcomes Following Breast-Conservation Surgery and Radiation for Multiple Ipsilateral Breast Cancer: Data from the Alliance Z11102 Study.
Ann Surg Oncol
November 2020
Department of Surgery, Mayo Clinic, Rochester, MN, USA.
Background: Diagnoses of multiple ipsilateral breast cancer (MIBC) are increasing. Historically, the primary treatment for MIBC has been mastectomy due to concerns about in-breast recurrence risk and poor cosmetic outcome. The Alliance Z11102 study prospectively assessed cosmetic outcomes in women with MIBC treated with breast-conserving therapy (BCT).
View Article and Find Full Text PDFMapping patterns of locoregional recurrence following contemporary treatment with radiation therapy for breast cancer: A multi-institutional validation study of the ESTRO consensus guideline on clinical target volume.
Radiother Oncol
January 2018
Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:
Background And Purpose: To validate the ESTRO guideline on clinical target volume (CTV) delineation for breast cancer using a multi-centre dataset.
Materials And Methods: Patients with axial imaging of gross locoregional recurrence (LRR) were identified from 10 participating institutions. All patients received RT, albeit not to all regional node.
Positive margins prediction in breast cancer conservative surgery: Assessment of a preoperative web-based nomogram.
Breast
August 2016
Medical Faculty of Porto University, Alameda Prof. Hernâni Monteiro, Porto 4200 - 319, Portugal; Breast Center, São João University Hospital, Alameda Prof. Hernâni Monteiro, Porto 4200 - 319, Portugal.
Margin status of the surgical specimen has been shown to be a prognostic and risk factor for local recurrence in breast cancer surgery. It has been studied as a topic of intervention to diminish reoperation rates and reduce the probability of local recurrence in breast conservative surgery (BCS). This study aims to validate the Dutch BreastConservation! nomogram, created by Pleijhus et al.
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