This study deciphers the topological sensitivity (TS) as a tool for the reconstruction and characterization of impenetrable anomalies in the high-frequency regime. It is assumed that the anomaly is simply connected and convex, and that the measurements of the scattered field are of the far-field type. In this setting, the formula for TS-which quantifies the perturbation of a cost functional due to a point-like impenetrable scatterer-is expressed as a pair of nested surface integrals: one taken over the boundary of a hidden obstacle, and the other over the measurement surface. Using multipole expansion, the latter integral is reduced to a set of antilinear forms featuring Green's function and its gradient. The remaining expression is distilled by evaluating the scattered field on the surface of an obstacle via Kirchhoff approximation, and pursuing an asymptotic expansion of the resulting Fourier integral. In this way, the TS is found to survive upon three asymptotic lynchpins, namely (i) the near-boundary approximation for sampling points close to the 'exposed' surface of an obstacle; (ii) uniform expansions synthesizing the diffraction catastrophes for sampling points near caustic surfaces, lines and points; and (iii) stationary phase approximation. Within the framework of catastrophe theory, it is shown that, in the case of the full source aperture, the TS is asymptotically dominated by the (explicit) near-boundary term-which explains the previously reported reconstruction capabilities of this class of indicator functionals. The analysis further shows that, when the (Dirichlet or Neumann) character of an anomaly is unknown beforehand, the latter can be effectively exposed by assuming point-like Dirichlet perturbation and considering the sign of the leading term inside the reconstruction.
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http://dx.doi.org/10.1098/rspa.2015.0187 | DOI Listing |
Nanophotonics
January 2025
Department of Electronic Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
Topological insulators and bound states in the continuum represent two fascinating topics in the optical and photonic domain. The exploration of their interconnection and potential applications has emerged as a current research focus. Here, we investigated non-Hermitian photonics based on a parallel cascaded-resonator system, where both direct and indirect coupling between adjacent resonators can be independently manipulated.
View Article and Find Full Text PDFDosage-sensitive transcription factors (TFs) underlie altered gene regulation in human developmental disorders, and cell-type specific gene regulation is linked to the reorganization of 3D chromatin during cellular differentiation. Here, we show dose-dependent regulation of chromatin organization by the congenital heart disease (CHD)- linked, lineage-restricted TF TBX5 in human cardiomyocyte differentiation. Genome organization, including compartments, topologically associated domains, and chromatin loops, are sensitive to reduced dosage in a human model of CHD, with variations in response across individual cells.
View Article and Find Full Text PDFChemistry
January 2025
National Chi Nan University, Department of Applied Chemistry, TAIWAN.
Three fluorescent Zn coordaintion polymers (CPs) have been synthesized from the reactions of Zn(NO3)2∙6H2O, benzene-1,4-dicarboxylic acid (1,4-H2bdc), and angular carbazole-derived bispyridyl ligands (Cz-3,6-bpy or Cz-Pr-3,6-bpy). CPs 1-3 all adopt similar two-dimensional (2D) ring-and-rod layer structures, described as topologically 4-connected 2∙65 nets where the Zn(II) centers act as 4-connected nodes. CPs 1 and 2 are a pair of solvent-mediated supramolecular isomers where the former shows a two-fold interlocked 2D → 2D polyrotaxane-like entangled net and the latter reveals a four-fold interpenetrated 2D → 3D polyrotaxane entanglement.
View Article and Find Full Text PDFUltrasonics
January 2025
New Frontiers of Sound Science and Technology Center, University of Arizona, Tucson, AZ 85721, USA; Department of Materials Science and Engineering, University of Arizona, Tucson, AZ 85721, USA.
We demonstrate an integrated non-destructive inspection methodology that employs the nonlinear ultrasonics-based sideband peak counting (SPC) technique in conjunction with topological acoustics (TA) sensing to comprehensively characterize the acoustic response of steel plates that contain differing levels of damage. By combining the SPC technique and TA, increased sensitivity to defect/damage detection as well as the ability to spatially resolve the presence of defects was successfully established. Towards this end, using a Rockwell hardness indenter, steel plates were subject to one, three and five centrally located indentations respectively.
View Article and Find Full Text PDFNat Mater
January 2025
Mechanisms of Morphogenesis Lab, Gulbenkian Institute of Science (IGC), Oeiras, Portugal.
Directed collective cell migration is essential for morphogenesis, and chemical, electrical, mechanical and topological features have been shown to guide cell migration in vitro. Here we provide in vivo evidence showing that endogenous electric fields drive the directed collective cell migration of an embryonic stem cell population-the cephalic neural crest of Xenopus laevis. We demonstrate that the voltage-sensitive phosphatase 1 is a key component of the molecular mechanism, enabling neural crest cells to specifically transduce electric fields into a directional cue in vivo.
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