Weanling cross-bred pigs (36 or 48) were caged individually and fed diets containing a supplement of vitamin A (Expt 1) or vitamin D3 (Expt 2) at levels representing 1, 5, 10, 25, 50 and 100 times the NRC (1988) estimated requirements, for 4 weeks. Growth rate, feed intake and feed/gain ratio were not influenced significantly. In Expt 1 the plasma retinol concentrations were at 4 weeks, respectively, 31.7, 39.4, 43.2, 42.9, 44.4, and 46.3 micrograms/dl (P less than 0.05). In Expt 2, the plasma 25(OH)D3 concentrations were at 2 weeks, respectively, 22.5, 29.5, 35.7, 46.2, 79.9, 135.3 ng/ml (P less than 0.001). Histological examination of lung, stomach, kidney, liver and heart indicated no abnormalities, but focal microscopic lesions consistent with osteochondrosis were found in pigs receiving vitamin A at levels over 10 times the requirement. The incidence of osteochondrosis at 2 weeks was, respectively, 0/8, 0/8, 0/8, 0/8, 0/8, and 1/8, and at 4 weeks was, respectively, 0/8, 0/8, 0/8, 2/8, 2/8 and 2/8. The NRC (1988) estimate of the requirement for vitamin D may be somewhat low since the concentration of plasma 25(OH)D was lower with 200 or 1,000 IU vitamin D/kg diet than at the start.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Double Fortified Salt Containing Iodine and Folic Acid and Triple Fortified Salt Containing Iodine, Folic Acid, and Vitamin B Are Acceptable to Ethiopian Women of Reproductive Age.
Food Sci Nutr
January 2025
Department of Nutrition and Institute for Global Nutrition University of California, Davis Davis California USA.
Recognizing the broader accessibility of iodized salt compared to wheat flour, the Ethiopian government is considering fortification of iodized salt with folic acid, and possibly vitamin B, to address the high incidence of neural tube defects (NTDs) in Ethiopia. To prepare for this program, we assessed practices related to edible salt procurement and consumption, and the acceptability of novel salts fortified with iodine and folic acid (double-fortified salt, DFS) or iodine, folic acid, and vitamin B (triple-fortified salt, TFS) compared to iodized salt (IS). We surveyed 840 women of reproductive age in urban (Addis Ababa) and rural (Gimbichu Woreda) areas to describe their salt preferences and practices and used a three-point hedonic scale to evaluate the sensory acceptability of fine and coarse forms of DFS, TFS, and IS for color, taste, aroma, texture and overall acceptability.
View Article and Find Full Text PDFIncidence of and Factors Associated with Spontaneous Correction of Postoperative Shoulder Imbalance in Adolescent Idiopathic Scoliosis Patients: A Retrospective Cohort Study.
Indian J Orthop
February 2025
Department of Orthopaedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, 10700 Bangkok Thailand.
Background: As far as we know, no study has investigated spontaneous postoperative shoulder imbalance (PSI) correction in adolescent idiopathic scoliosis (AIS) patients. The objective is to assess the incidence of and associated factors for spontaneous PSI correction in AIS patients.
Methods: The study evaluated 144 postoperative AIS patients with PSI aged 10-20 years between 2010 and 2018.
Objective: The Cancer and Aging Research Group (CARG) score was developed to predict severe chemotherapy-induced toxicity risk in older adults; validation study results have varied. The Tolerance of Anti-cancer Systemic Therapy in the Elderly study sought to evaluate the CARG score prospectively in a chemotherapy-naïve UK population.
Methods And Analysis: This multicentre, prospective, observational study recruited patients aged ≥65 years commencing first-line chemotherapy for any solid organ malignancy or setting.
Detection of Hepatitis C Virus Infection in Patients Undergoing Open Heart Surgery in Childhood Prior to 1992: A Danish Nationwide Cross-Sectional Study.
Clin Med Insights Pediatr
January 2025
Department of Cardiothoracic Surgery, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Background And Aim: Pediatric patients undergoing cardiac surgery prior to 1992 in Denmark were at risk of hepatitis C virus (HCV) infection through donor blood used in extracorporeal circulation. HCV screening became possible in donors in 1991, eliminating the risk of iatrogenic infections. No formalized screening has been conducted for patients receiving non-screened blood, potentially leaving some with undetected HCV infection.
View Article and Find Full Text PDFRemoval of active pharmaceutical compounds in Primalan and Diane using pumpkin biochar: synthesis, characterization, and adsorption study.
RSC Adv
January 2025
Research Laboratory in Subterranean and Surface Hydraulics, University of Biskra PO Box 145 RP Biskra Algeria.
This investigation aims to apply the adsorption process to eliminate mequitazine and ethinylestradiol, the active molecules of Primalan and Diane, respectively, from aqueous solutions, utilizing biochar synthesized from pumpkin fruits (PB-500). The results revealed that the obtained adsorbent possessed a notable specific surface area, contributing to removal efficiencies of 66.61% and 62.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!