AI Article Synopsis

  • The study targeted the effectiveness of posterior sub-Tenon triamcinolone acetonide (PSTA) in treating branch retinal vein occlusion (BRVO) macular edema.
  • Patients received a single dose of 40 mg PSTA and were monitored for changes in vision and macular thickness over six months.
  • Results showed significant improvements in visual acuity and central macular thickness within the first three months, with minimal side effects, indicating that PSTA is both effective and safe for this condition.

Article Abstract

Objective: To investigate the effectiveness and reliability of posterior sub-Tenon triamcinolone acetonide (PSTA) application in branch retinal vein occlusion (BRVO)-related macular edema.

Methods: Patients with confirmed BRVO-related macular edema were enrolled in the study. Patients were injected with a single, therapeutic dose of 40 mg PSTA. Detailed ophthalmic examination was performed at baseline and at 1, 3 and 6 months after the treatment. Best corrected visual acuity (BCVA), intraocular pressure (IOP), cataractogenic change (CC) and macular optical coherence tomography (OCT) analysis results were evaluated. The results were compared statistically.

Results: Forty-one eyes of 41 patients with a mean age of 63.49 ± 10.99 (55-86) years, 15 (36.6%) females, were included in the study. BCVA in LogMAR values at 1 and 3 months were significantly better than at baseline, while no significant difference from baseline was observed in sixth month values (p < 0.001, p < 0.001 and p = 0.846, respectively). Central macular thickness values obtained using OCT were significantly lower at the first, third and sixth months compared to baseline (p < 0.001 for all). IOP elevation was determined in only two eyes (4.8%) at the end of the study period, and no CC was detected in any case.

Conclusion: PSTA application is an effective and safe option in BRVO-related macular edema.

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Source
http://dx.doi.org/10.3109/15569527.2015.1074586DOI Listing

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