Intrauterine Treatment of a Fetus with Familial Hypertrophic Cardiomyopathy Secondary to MYH7 Mutation.

Pediatr Cardiol

Department of Obstetrics and Gynecology, The University of Arizona, College of Medicine, 1501 N. Campbell Ave, 8th Floor, Tucson, AZ, 85724, USA.

Published: December 2015

There is no clear consensus on optimal management of fetuses affected by familial hypertrophic cardiomyopathy (HCM). Intrauterine treatment of the condition has not been attempted in any standardized fashion. We report the case of a fetus treated by maternal propranolol during the third trimester after septal hypertrophy and diastolic dysfunction was diagnosed on fetal echocardiogram. The pregnancy went successfully to term, and fetal septal hypertrophy was noted to improve prior to delivery.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655206PMC
http://dx.doi.org/10.1007/s00246-015-1250-1DOI Listing

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