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Global epidemiology and clinical outcomes of carbapenem-resistant Pseudomonas aeruginosa and associated carbapenemases (POP): a prospective cohort study.
Lancet Microbe
March 2023
Division of Infectious Diseases, Weill Cornell Medicine, New York, NY, USA. Electronic address:
Background: Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a global threat, but the distribution and clinical significance of carbapenemases are unclear. The aim of this study was to define characteristics and outcomes of CRPA infections and the global frequency and clinical impact of carbapenemases harboured by CRPA.
Methods: We conducted an observational, prospective cohort study of CRPA isolated from bloodstream, respiratory, urine, or wound cultures of patients at 44 hospitals (10 countries) between Dec 1, 2018, and Nov 30, 2019.
Diphtheria And Tetanus Vaccination History Is Associated With Lower Odds of COVID-19 Hospitalization.
Front Immunol
November 2021
NORMENT, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Background: COVID-19 is characterized by strikingly large, mostly unexplained, interindividual variation in symptom severity: while some individuals remain nearly asymptomatic, others suffer from severe respiratory failure. Previous vaccinations for other pathogens, in particular tetanus, may partly explain this variation, possibly by readying the immune system.
Methods: We made use of data on COVID-19 testing from 103,049 participants of the UK Biobank (mean age 71.
[CME. Pertussis]].
Praxis (Bern 1994)
September 2015
1 Klinik und Poliklinik für Innere Medizin, Universitätsspital Zürich.
Influenza and tetanus, diphtheria, and acellular pertussis vaccinations during pregnancy.
Obstet Gynecol Surv
April 2012
Department Obstetrics and Gynecology, Vanderbilt University, Nashville, TN, USA.
Unlabelled: Vaccinations in pregnancy are an important aspect of prenatal care and of improving not only maternal health but also neonatal outcomes. Only 2 vaccines are specifically recommended during pregnancy: influenza and tetanus, diphtheria, and acellular pertussis (Tdap). Because influenza illness disproportionately affects pregnant women compared with other populations, annual prevention of influenza illness is recommended for all women who will be pregnant during influenza season (October to May).
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