AI Article Synopsis
- A 79-year-old woman with a lung mass was referred to the hospital after treatment for pneumonia revealed a persistent abnormal shadow on a chest x-ray.
- A chest CT scan identified a 7.6 cm solid mass likely invading the superior pulmonary vein, leading to a successful right pneumonectomy.
- Pathological analysis revealed the tumor to be a collision cancer made up of poorly differentiated squamous cell carcinoma and invasive adenocarcinoma, both showing the same EGFR mutation, suggesting they may have originated from the same source.
Article Abstract
We report a 79-year-old woman with collision cancer in the right middle lobe of the lung. She had a persistent abnormal shadow after treatment for pneumonia pointed out in right middle lung field on chest radiogram, and referred to our hospital. On examination, the chest computed tomography showed a pure-solid mass of 7.6 cm in diameter in right middle lobe of the lung which was thought to invade the superior pulmonary vein. She underwent a successful right pneumonecomty, and the postoperative course was uneventful. The tumor proved to be a collision cancer consisting of poor differentiated squamous cell carcinoma and invasive adenocarcinoma, lepidic predominanat by pathological examination. Epidermal growth factor receptor mutations (L858R) were found in both squamous cell carcinoma and adenocarcinoma of the tumor, possibly suggesting the same origin of both histological types.
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