Patterns and clinical manifestations of tuberculous myocarditis: a systematic review of cases.

Pan Afr Med J

School of Medicine, University of Nairobi, Nairobi 00100, Kenya ; Department of Medical Physiology, University of Nairobi, Nairobi 00100, Kenya.

Published: June 2016

Tuberculosis is a rare cause of myocarditis. It is however associated with a high mortality when it occurs and is often diagnosed at post-mortem. Tuberculous myocarditis prevalence in males is twice that in females. Most of the reported cases of tuberculous myocarditis are predominantly in immunocompetent patients. Out of the reported fatalities (sudden cardiac deaths), eighty one percent (81%) occur in the 'young' patients (below 45years). Antituberculosis drug therapy does not appear to offer mortality benefit against sudden cardiac deaths.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546727PMC
http://dx.doi.org/10.11604/pamj.2015.21.118.4282DOI Listing

Publication Analysis

Top Keywords

tuberculous myocarditis
12
sudden cardiac
8
cardiac deaths
8
patterns clinical
4
clinical manifestations
4
manifestations tuberculous
4
myocarditis
4
myocarditis systematic
4
systematic review
4
review cases
4

Similar Publications

Objectives: We present a case series of patients with granulomatous myocarditis presenting as atrial arrhythmias accompanied by lymphadenopathy.

Background: Atrial myocarditis (AM) may be the cause of atrial fibrillation (AF) in patients without risk factors.

Methods: Patients with atrial fibrillation without risk factors underwent 18F-Fluorodeoxyglucose positron emission tomography (18F-FDG-PET).

View Article and Find Full Text PDF

Pulmonary tuberculosis presenting with tubercular myocarditis and shock in an adolescent child.

J Family Med Prim Care

December 2024

Department of Pediatrics, PGIMS, Rohtak, Haryana, India.

Involvement of the heart in children with tuberculosis (TB) generally affects the pericardium; however, the myocardium of a child being affected alone and leading to systolic heart dysfunction has rarely ever been reported. We report a case of a 12-year-old child who presented to Pediatric Emergency Services with severe hypotension (BP <5 percentile for the age) and was subsequently diagnosed with severe left ventricular (LV) dysfunction, with an ejection fraction of less than 15%. During the hospital stay, after an exhaustive workup, the child was diagnosed with pulmonary TB with tubercular myocarditis.

View Article and Find Full Text PDF

Background: Eosinophilic myocarditis is a life-threatening condition with a heterogeneous clinical presentation and aetiology. Cases of drug-induced or parasitic myocarditis have been reported but there is scant literature on the involvement of treatments, such as doxycycline, and eosinophil degranulation due to parasitic lysis.

Case Summary: Here, we report the case of a 59-year-old man without a relevant past medical history who developed a skin rash with hepatic cytolysis and mild eosinophilia.

View Article and Find Full Text PDF
Article Synopsis
  • * Cardiologists are seeing more complications from acute viral pericarditis, leading to chronic or recurrent cases, which are more common today than a few years ago.
  • * The European guidelines for pericarditis management, last updated a decade ago, are set to be revised soon, and insights were gathered from Massimo Imazio, a leading expert in inflammatory heart diseases, regarding pressing management questions.
View Article and Find Full Text PDF

Icariin ameliorates Coxsackievirus B3-induced viral myocarditis by modulating the S100 calcium binding protein A6/β-catenin/c-Myc signaling pathway.

Phytomedicine

December 2024

The First Affiliated Hospital of Nanchang University and School of Basic Medical sciences, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China. Electronic address:

Background: Coxsackievirus B3 (CVB3) is a leading cause of viral myocarditis and is currently lacking specific pharmacological treatments, highlighting the critical need for therapeutic development. Icariin (ICA), a prenylated flavonol glycoside, was previously found to exhibit several pharmacological effects, but its potential to combat CVB3 remains uninvestigated.

Purpose: This study aimed to elucidate the anti-CVB3 efficacy of ICA and elucidate its molecular mechanisms.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!