These guidelines are intended for use by infectious disease specialists, orthopedic surgeons, neurosurgeons, radiologists, and other healthcare professionals who care for patients with native vertebral osteomyelitis (NVO). They include evidence and opinion-based recommendations for the diagnosis and management of patients with NVO treated with antimicrobial therapy, with or without surgical intervention.
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| http://dx.doi.org/10.1093/cid/civ633 | DOI Listing |
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Three-Dimensional Printing of Bioinspired Hierarchical Structures for Enhanced Fog Collection Efficiency in 3D Space via Vat Photopolymerization.
Biomimetics (Basel)
December 2024
Department of Mechanical Engineering, San Diego State University, San Diego, CA 92182, USA.
Collecting fog water is crucial for dry areas since natural moisture and fog are significant sources of freshwater. Sustainable and energy-efficient water collection systems can take a page out of the cactus's playbook by mimicking its native fog gathering process. Inspired by the unique geometric structure of the cactus spine, we fabricated a bioinspired artificial fog collector consisting of cactus spines featuring barbs of different sizes and angles on the surfaces for water collection and a series of microcavities within microchannels inspired by Nepenthes Alata on the bottom to facilitate water flowing to the reservoir.
View Article and Find Full Text PDFBiomimetic Proteoglycans for Intervertebral Disc (IVD) Regeneration.
Biomimetics (Basel)
November 2024
Spine Service & Spine Labs, St George & Sutherland School of Clinical Medicine, Faculty of Health and Medicine, University of New South Wales, Kogarah, NSW 2217, Australia.
Intervertebral disc degeneration, which leads to low back pain, is the most prevalent musculoskeletal condition worldwide, significantly impairing quality of life and imposing substantial socioeconomic burdens on affected individuals. A major impediment to the development of any prospective cell-driven recovery of functional properties in degenerate IVDs is the diminishing IVD cell numbers and viability with ageing which cannot sustain such a recovery process. However, if IVD proteoglycan levels, a major functional component, can be replenished through an orthobiological process which does not rely on cellular or nutritional input, then this may be an effective strategy for the re-attainment of IVD mechanical properties.
View Article and Find Full Text PDFChange in standing acetabular orientation 2 years postoperatively after surgical correction of adult spinal deformity.
Orthop Traumatol Surg Res
December 2024
Arts et Métiers ParisTech, 151 Boulevard de l'Hôpital, 75013 Paris, France.
Introduction: Although sagittal alignment is known to influence pelvic position, few studies accurately identify the relationship between sagittal alignment and acetabular orientation. We hypothesized that postoperative PT should be correlated with acetabular change in native hips after surgical correction of adult spinal deformity. The objective of this study was therefore to describe the correlation between the change in pelvic tilt and the change in acetabular orientation two years after surgical correction of adult spinal deformity.
View Article and Find Full Text PDF[Biodegradable devices for annulus fibrosus defect closure after lumbar discectomy].
Khirurgiia (Mosk)
December 2024
Kurchatov Institute, Moscow, Russia.
Objective: To study the properties of materials and select the most suitable one for appropriate device covering annulus fibrosus defect after lumbar discectomy.
Material And Methods: Prototype devices made of poly(L-)lactide, polycaprolactone (PLC) and copolymers of(L-)lactide and ε-caprolactone (LCL) without prior purification were used. Sponge materials were prepared using 1.
Restoration of physiologic loading after engineered disc implantation mitigates immobilization-induced facet joint and paraspinal muscle degeneration.
Acta Biomater
December 2024
Department of Orthopaedic Surgery, McKay Orthopaedic Research Laboratory, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA. Electronic address:
Intervertebral disc degeneration is commonly associated with back and neck pain, and standard surgical treatments do not restore spine function. Replacement of the degenerative disc with a living, tissue-engineered construct has the potential to restore normal structure and function to the spine. Toward this goal, our group developed endplate-modified disc-like angle-ply structures (eDAPS) that recapitulate the native structure and function of the disc.
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