AI Article Synopsis

  • The primary drainage for breast lymphatics typically occurs in the same-side axilla, but some patients may experience drainage to other areas like the internal mammary chain or rarely, the opposite axilla.
  • A case study is presented involving a patient with untreated right breast cancer showing contralateral axillary drainage, leading to additional surgical dissection after detection of micrometastasis in the sentinel lymph node.
  • Post-surgery, while most ipsilateral lymph nodes showed cancer spread, the majority of contralateral lymph nodes were nonmetastatic, highlighting the importance of assessing contralateral axillary involvement in cancer staging and management.

Article Abstract

The main basin for breast lymphatic drainage is ipsilateral axilla. However, extra-axillary drainage may be seen in some patients. The most common extra-axillary site is internal mammary chain, while contralateral axillary drainage is an extremely rare situation in previously untreated patients. We describe a case of untreated right breast retroareolar carcinoma with contralateral axillary drainage detected on preoperative lymphoscintigraphy. Contralateral axillary dissection was performed based on the result of frozen section examination of the sentinel lymph node (SLN) which turned out to burden micrometastasis. Postoperative histopathological examination revealed invasive ductal carcinoma metastasis in 17 out of 22 lymph nodes from the ipsilateral axillary dissection, whereas 14 lymph nodes from contralateral axillary dissection other than the SLN were nonmetastatic. In our opinion, determination of contralateral axillary metastasis in primary staging process had a major contribution to the management of the patient.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563177PMC
http://dx.doi.org/10.4274/mirt.91300DOI Listing

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