Chronic Kidney Disease and Related Long-Term Complications After Liver Transplantation.

Adv Chronic Kidney Dis

Division of Gastroenterology, University of Michigan, Ann Arbor, MI; Division of Gastroenterology, University of Cincinnati, Cincinnati, OH.

Published: September 2015

Liver transplantation is the standard of care for patients with decompensated cirrhosis. Liver transplantation recipients have excellent short-term and long-term outcomes including patient and graft survival. Since the adoption of model for end-stage liver disease (MELD)-based allocation policy, the incidence of post-transplant end stage renal disease has risen significantly. Occurrence of Stage 4 chronic kidney disease and end stage renal disease substantially increases the risk of post-transplant deaths. Because majority of late post-transplant mortality is due to nonhepatic post-transplant comorbidities, personalized care directed toward risk factor modification may further improve post-transplant survival.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556126PMC
http://dx.doi.org/10.1053/j.ackd.2015.06.001DOI Listing

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