The article is devoted to the results of the treatment of 264 children with hematogenic osteomyelitis. The analysis of the changes of the extremities length growth depending on the children's age, the form of the disease, the localization of the osteomyelitic process and the administered treatment is presented. The authors have proposed a new method of stimulating the growth of the shortened tubular bones in cases of difference in the length of the extremities up to 3 cm in the children of the younger age group.
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Pathol Res Pract
March 2024
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
Osteomyelitis, a debilitating bone infection, presents considerable clinical challenges due to its intricate etiology and limited treatment options. Despite strides in surgical and chemotherapeutic interventions, the treatment landscape for osteomyelitis remains unsatisfactory. Recent attention has focused on the role of non-coding RNAs (ncRNAs) in the pathogenesis and progression of osteomyelitis.
View Article and Find Full Text PDFJ Craniofac Surg
June 2021
Department of Plastic Surgery, Hackensack University Medical Center, Hackensack.
Craniosynostosis, a deformity of the skull caused by premature fusion of ≥1 cranial sutures, is treated surgically via endoscopic approaches or cranial vault remodeling. Postoperative infection is rare. Management of postoperative surgical site infections often involves culture-directed intravenous antibiotics and debridement, with removal of osteomyelitic bone and hardware in refractory cases.
View Article and Find Full Text PDFItal J Pediatr
July 2020
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via F. Sforza 35,20122, Milan, Italy.
Background: Complications of acute sinusitis affecting multiple sites are very uncommon, and generally develop for a delayed diagnosis of the primary infection, with possible severe and life-threatening evolution. Patients can have variable presentations according to the site and extent of the infection. Multiple forms generally include the coexistence of orbital manifestations and intracranial infections.
View Article and Find Full Text PDFInjury
October 2021
Hand and Microsurgery & Orthopedics and Traumatology (EMOT) Hospital, 1418 Sok. No: 14 Kahramanlar, 35230 Izmir, Turkey.
Large segmental bone defects due to major trauma constitute a major challenge for the orthopaedic surgeon, especially when combined with poor or lost soft tissue envelope. Vascularized fibular transfer is considered as the gold standard for the reconstruction of such defects of the extremities due to its predictable vascular pedicle, long cylindrical shape, and tendency to hypertrophy, and resistance to infection. Vascularized bone grafts remain viable throughout the healing period and are capable of inducing rapid graft union without prolonged creeping substitution, osteogenesis and hypertrophy at the reconstruction site, and fight with infection.
View Article and Find Full Text PDFContrast Media Mol Imaging
July 2019
Turku PET Centre, University of Turku, Turku, Finland.
There may be some differences in the behavior of Ga-chloride and Ga-citrate leading to different accumulation profiles. This study compared Ga-citrate and Ga-chloride PET/CT imaging under standardized experimental models. Diffuse tibial osteomyelitis and uncomplicated bone healing rat models were used ( = 32).
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