Asymptomatic mitral regurgitation-wait or operate?

Ann Cardiothorac Surg

1 The Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia ; 2 Department of Cardiothoracic Surgery, Prince of Wales Hospital, Sydney, New South Wales, Australia.

Published: July 2015

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526503PMC
http://dx.doi.org/10.3978/j.issn.2225-319X.2015.03.09DOI Listing

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Article Synopsis
  • The left atrium (LA) plays an active role in heart function, and its impaired compliance in severe mitral regurgitation (MR) can lead to increased pressures and symptoms like dyspnea.
  • This study analyzes LA function in patients with severe degenerative MR to see how it correlates with symptom onset, classifying patients into symptomatic and asymptomatic groups.
  • Results indicate that LA dysfunction is significantly linked to symptoms, with a specific marker (LASr) being a strong predictor, suggesting that recognizing LA dysfunction can help manage asymptomatic patients effectively.
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