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Innovative use of the new pulsed-thulium: YAG laser for ureteroscopic lithotripsy: can the "kidney stone calculator" predict lithotripsy duration?
Urolithiasis
December 2024
Groupe de Recherche Clinique sur la Lithiase Urinaire, GRC n°20, Hôpital Tenon, Sorbonne Université, Paris, 75020, France.
To assess the accuracy of Kidney Stone Calculator(KSC), a software designed for surgical planning, in predicting the duration of lithotripsy during flexible ureteroscopy(FURS) when using the novel pulsed-Thulium: YAG(p-Tm: YAG) laser. From February to August 2023, a single-center prospective study was conducted, including patients with kidney or ureteral stones through non-contrast computed tomography(NCCT), who underwent FURS with p-Tm: YAG laser lithotripsy. KSC used three-dimensional segmentation of the stones from NCCT images, along with an interactive user interface for laser settings, to estimate the stone volume(SV) and the lithotripsy duration(LD).
View Article and Find Full Text PDFUrinary Stone Composition Analysis of 1465 Patients: The First Series from Azerbaijan.
Arch Iran Med
November 2024
Department of Laboratory, State Security Service Military Hospital, Baku, Azerbaijan.
Article Synopsis
- - The study focuses on urinary stone disease in Azerbaijan, analyzing the composition of stones from 1,465 patients using FTIR spectroscopy over nearly a decade.
- - Findings indicate that calcium oxalate stones are the most common type at 56.2%, with uric acid stones following at 33.7%, and show variations based on age and gender.
- - The research suggests a need for customized diagnostic and treatment strategies due to the high prevalence of urinary stones, especially mixed types, highlighting the complexity of this health issue.
Medical dissolution of presumptive upper urinary tract struvite uroliths in 6 dogs (2012-2018).
J Vet Intern Med
November 2024
Department of Urology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Article Synopsis
- Minimally invasive treatments for upper urinary tract uroliths (kidney stones) are the standard in humans and this study explores their application in dogs.
- A total of 6 female dogs with various combinations of kidney and ureter stones were treated using dietary changes, antibiotics, and ureteral stenting, achieving significant urolith dissolution over several months.
- The results suggest that medical dissolution can be an effective strategy for treating struvite uroliths in dogs, potentially avoiding the need for more invasive surgical procedures.
Article Synopsis
- Urosepsis is a common complication following flexible ureterorenoscopy (F-URS), occurring in up to 4.3% of cases and accounting for significant healthcare costs.
- A study involving 486 F-URS procedures at eleven French centers evaluated clinical factors that increase the risk of urosepsis, identifying key risk indicators.
- Results indicated that a type IV calculus (carbapatite or struvite), along with factors like coronary insufficiency and larger stone size, significantly increase the risk of post-operative urosepsis, emphasizing the need for enhanced monitoring in these cases.
Comparison of cat stone matrix and cat urine proteomes to human calcium oxalate stone matrix and urine proteomes.
Urolithiasis
September 2024
Department of Urology, Department of Veterans Affairs Medical Center, Clement J Zablocki VA Medical Center, 5000 W National Avenue (111K), Milwaukee, WI, 53295, USA.
Article Synopsis
- A study compared the proteomes of calcium oxalate monohydrate kidney stones in cats and humans, revealing substantial similarities but limited analysis due to a lack of cat urine proteomic data.
- Urine proteome data from 7 healthy cats was gathered and compared to human urine and cat calcium oxalate stone matrices to identify shared enrichment patterns.
- The findings indicated that cat urine proteins showed distribution similarities to human urine, while differences in cat struvite stone matrices suggest distinct mechanisms of stone formation involving both protein interactions and crystal aggregation.
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