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Lupus Nephritis Patterns and Response to Type I Interferon in Patients With DNASE1L3 Variants: Report of Three Cases.
Am J Kidney Dis
December 2024
Nephrology and Dialysis Unit, Meyer Children's Hospital IRCCS, Firenze, Italy; Department of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Firenze, Firenze, Italy. Electronic address:
Article Synopsis
- * The study focuses on three children with monogenic systemic lupus erythematosus (SLE) due to DNASE1L3 variants who experienced severe kidney issues, showing different types of glomerulonephritis.
- * Findings revealed a connection between DNASE1L3-related kidney issues and interferon signaling, suggesting potential benefits of targeted interferon therapies to improve patient outcomes.
Overlap Syndrome of Diffuse Systemic Sclerosis, Sjögren Syndrome, and ANCA-Associated Renal-Limited Vasculitis: Three Entities in One Patient - Case Report.
Case Rep Nephrol Dial
March 2024
Nephrology Service, Hospital General de México, Mexico City, Mexico.
Introduction: The presence of three different entities in a single patient is usually of clinical interest and mostly anecdotal. The overlap of systemic sclerosis (SSc), Sjögren syndrome (SS), and ANCA-associated renal-limited vasculitis has been reported only once previously.
Case Presentation: A 61-year-old female was evaluated at consultation with 2 years of symptomatology, presenting cardboard-like skin, sclerodactyly, limited oral opening, and dry skin and eyes.
The need for renal biopsy in oncology patients on check-point inhibitors check-point inhibitors: New triggers for extracapillary glomerulonephritis extracapillary glomerulonephritis.
Nefrologia (Engl Ed)
December 2023
Hospital Clínico San Carlos, Ciudad Real, Spain.
ANCA-positive extracapillary proliferative glomerulonephritis associated with the administration of ustekinumab.
Med Clin (Barc)
February 2024
Sección de Nefrología, Hospital Universitario San Agustín, Avilés, Asturias, España.
IgA nephropathy in children with minimal proteinuria: to biopsy or not to biopsy?
Pediatr Nephrol
March 2024
Division of Nephrology, Hôpital Robert Debré, Paris, France.
Background: Tubulointerstitial lesions and glomerular inflammation severity have been shown to correlate with proteinuria in children with IgA nephropathy (cIgAN). However, there is a lack of data regarding severity of histopathologic findings in cIgAN in patients with minimal to absent proteinuria since kidney biopsy indications are not well defined in these cases.
Methods: Twenty-eight cIgAN patients with kidney biopsy from 4 different centers in Paris (France) and Montreal (Canada) with a urine protein/creatinine ratio (UPCr) ≤ 0.
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