[Enophthalmos as a first sign of breast cancer].

Ned Tijdschr Geneeskd

Academisch Medisch Centrum, afd. Oogheelkunde, Amsterdam.

Published: July 2016

Background: Metastasis of breast carcinoma to the orbit is characterized by symptoms of altered appearance and double vision. A combination of enophthalmos, ptosis and impairment of eye movements is typical. Sometimes these symptoms are the first manifestation of breast carcinoma.

Case Description: Two female patients, aged 66 and 52, presented with enophthalmos. Both had recently undergone mammography with no abnormalities being observed. CT scans of these patients disclosed an intra-orbital, space-occupying process. Histological examination of biopsies from the abnormal tissue revealed that both patients had metastatic breast carcinoma.

Conclusion: In a female patient with non-traumatic enophthalmos, metastasis of breast carcinoma must be ruled out and reliance may not be placed on a mammogram revealing no abnormalities.

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