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Immobilization of biofunctional molecule with potential osteoinductive efficacy on titanium implant for promoting early-stage osseointegration.
J Craniomaxillofac Surg
January 2025
Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Ishikawa 920-0293, Japan.
In the present study, porcine-derived collagen type I was covalently immobilized on the surface of titanium (Ti) implants via carboxyl groups introduced by bonded p-vinylbenzoic acid to investigate its in vitro biocompatibility with gingival stem cells and in vivo bone regeneration behavior in the edentulous ridges of Lanyu small-ear pigs at weeks 2 and 6 (short-term effectiveness) through micro-computed tomography and histological analysis. Analytical results found that gingival stem cells showed effective adhesion and spreading on these collagen-immobilized implant surfaces. After 2 and 6 weeks of healing, significant differences in Hounsfield units were observed among the control (week 2 (674.
View Article and Find Full Text PDFA Scientometric Exploration of the Socket-shield Technique in Oral Implantology: Trends and Spatiotemporal Dynamics.
J Contemp Dent Pract
October 2024
Department of Academic, Grupo de Bibliometría, Evaluación De Evidencia y Revisiones Sistemáticas (BEERS), Human Medicine Career, Faculty of Medicine, Universidad Científica del Sur, Lima, Peru, Phone: +5113171023, e-mail:
Aim: The socket-shield technique arises from the efforts to stop the dimensional changes of the bone crest and gingival tissues. This technique consists of leaving a vestibular fragment of a naturally attached root with the purpose of keeping the crestal bone nourished through the periodontium. The aim of this research was to perform a scientometric analysis of the scientific production on the socket-shield technique in oral implantology.
View Article and Find Full Text PDFAccuracy of the over-preparation technique in implant surgery in the maxillary anterior region: an in vitro study.
BMC Oral Health
January 2025
Department of Oral Implantology, The Affiliated Stomatological Hospital of Xuzhou Medical University, 130 Huaihai West Road, Xuzhou, 221003, PR China.
Background: In the maxillary anterior region, differences in bone density along the drilling path can impact the accuracy of implant placement despite the use of a surgical guide. Hence, the aim of this in vitro study was to investigate the accuracy of implant placement using the over-preparation technique in different drilling environments in the maxillary anterior region.
Methods: Three experimental models (a, b, and c) were designed and fabricated to simulate the following drilling environments (n = 60 each): unhealed bone, less dense bone, and dense bone after tooth extraction.
A biodegradable magnesium alloy promotes subperiosteal osteogenesis via interleukin-10-dependent macrophage immunomodulation.
Biomaterials
December 2024
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China; Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices& Beijing Key Laboratory of Digital Stomatology & NHC Key Laboratory of Digital Stomatology & NMPA Key Laboratory for Dental Materials, Beijing, China. Electronic address:
In situ bone regeneration and vertical bone augmentation have been huge problems in clinical practice, always imposing a significant economic burden and causing patient suffering. Herein, MgZnYNd magnesium alloy rod implantation in mouse femur resulted in substantial subperiosteal new bone formation, with osteoimmunomodulation playing a pivotal role. Abundant macrophages were attracted to the subperiosteal new bone region and proved to be the most important regulation cells for bone regeneration.
View Article and Find Full Text PDFImproved Biomineralization Using Cellulose Acetate/Magnetic Nanoparticles Composite Membranes.
Polymers (Basel)
January 2025
Department of Dental Medicine and Nursing, Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.
Following implantation, infections, inflammatory reactions, corrosion, mismatches in the elastic modulus, stress shielding and excessive wear are the most frequent reasons for orthopedic implant failure. Natural polymer-based coatings showed especially good results in achieving better cell attachment, growth and tissue-implant integration, and it was found that the inclusions of nanosized fillers in the coating structure improves biomineralization and consequently implant osseointegration, as the nanoparticles represent calcium phosphate nucleation centers and lead to the deposition of highly organized hydroxyapatite crystallites on the implant surface. In this study, magnetic nanoparticles synthesized by the co-precipitation method were used for the preparation of cellulose acetate composite coatings through the phase-inversion method.
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