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| http://dx.doi.org/10.1017/S0950268815001946 | DOI Listing |
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Coordinated human-exoskeleton locomotion emerges from regulating virtual energy.
PLoS One
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Department of Mechanical and Mechatronics Engineering, University of Waterloo, Waterloo, ON, Canada.
Lower-limb exoskeletons have demonstrated great potential for gait rehabilitation in individuals with motor impairments; however, maintaining human-exoskeleton coordination remains a challenge. The coordination problem, referred to as any mismatch or asynchrony between the user's intended trajectories and exoskeleton desired trajectories, leads to sub-optimal gait performance, particularly for individuals with residual motor ability. Here, we investigate the virtual energy regulator (VER)'s ability to generate coordinated locomotion in lower limb exoskeleton.
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Asian School of the Environment and Earth Observatory of Singapore, Nanyang Technological University, Singapore.
As Water Sensitive Urban Design (WSUD) is a key strategy in integrated urban water management worldwide, there is a need for robust monitoring of WSUD systems. Being economical and flexible for operation and communication, low-cost sensor systems show great potential to mainstream digital water management. Yet, such systems are insufficiently tested, casting doubt on the reliability of their measurements.
View Article and Find Full Text PDFIdentification of ALEKSIN as a novel multi-IRF inhibitor of IRF- and STAT-mediated transcription in vascular inflammation and atherosclerosis.
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Human Molecular Genetics Research Unit, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Poznan, Poland.
Cardiovascular diseases (CVDs) include atherosclerosis, which is an inflammatory disease of large and medium vessels that leads to atherosclerotic plaque formation. The key factors contributing to the onset and progression of atherosclerosis include the pro-inflammatory cytokines interferon (IFN)α and IFNγ and the pattern recognition receptor (PRR) Toll-like receptor 4 (TLR4). Together, they trigger the activation of IFN regulatory factors (IRFs) and signal transducer and activator of transcription (STAT)s.
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School of Education and Sciences, University of Gloucestershire, Gloucester, UK, UK.
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Multi-gene precision editing tool using CRISPR-Cas12a/Cpf1 system in Ogataea polymorpha.
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National Center of Technology Innovation for Synthetic Biology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
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