AI Article Synopsis
- Precision medicine is focused on tailoring healthcare to individual patients by considering both their unique biology and clinical symptoms, which leads to a wealth of unanalyzed biological data.
- The 'New Disease Management Model' aims to standardize the integration of various data platforms to help create new disease taxonomies and personalize treatment based on genetic profiles.
- Recent advancements in precision therapy have shown improved efficacy in clinical trials, with future drug development targeting disease subtypes for greater specificity, efficacy, and reduced toxicity.
Article Abstract
Precision medicine allows a dramatic expansion of biological data, while there is still an urgent need to understand and insight the exact meaning of those data to human health and disease. This has led to an increasing wealth of data unanalyzed. The concept of precision medicine is about the customization of healthcare, with decisions and practices tailored to an individual patient based on their intrinsic biology in addition to clinical "signs and symptoms". Construction of a standardized model for the integration of data from various platforms is the central mission of the 'New Disease Management Model'. The model is helpful for the development of new taxonomy of diseases and subtypes, to personalize therapy based on patient genetic profiles. A rapid progression of precision therapy has been made recently. Clinical trials have shown the therapeutic efficacy of discovered and developed therapeutic agents has improved. However, next-generation drugs would be designed for disease subtypes with more specificity, efficacy and lower toxicity.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547974 | PMC |
| http://dx.doi.org/10.1186/s40169-015-0069-y | DOI Listing |
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