Context: Patients presenting with heart failure symptoms are categorized into heart failure (HF) with reduced and preserved ejection fraction.
Objective: Aim is to investigate the additional use of candidate biomarkers to characterize patients with either sub-type of HF.
Methods: Literature search was conducted in the electronic databases MEDLINE and Cochrane Central Register of Controlled Trials from inception through November 2014.
Results: The results of 47 diseased and general population cohorts were included.
Conclusion: Current studies could outline the additional use of candidate biomarkers especially GDF-15, MR-proADM and high-sensitive determined troponin, although major outcome studies are still missing.
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| http://dx.doi.org/10.3109/1354750X.2015.1068856 | DOI Listing |
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