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Experimental animal models and their use in understanding cysticercosis: A systematic review.
PLoS One
July 2022
Department of Clinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia.
Background: Cysticercosis and Neurocysticercosis (NCC) can be studied using several animal species in experimental models which contributes to the understanding of the human form of the disease. Experimental infections of Taenia spp. are vital in explaining the modes of transmission of the parasite and helps the understanding of transmission of the parasite in humans and thus may be useful in designing therapeutic and immune-prophylactic studies to combat the disease.
View Article and Find Full Text PDFAdvances in the treatment, diagnosis, control and scientific understanding of taeniid cestode parasite infections over the past 50 years.
Int J Parasitol
December 2021
Ulm University Hospital, Division of Infectious Diseases, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
In the past 50 years, enormous progress has been made in the diagnosis, treatment and control of taeniid cestode infections/diseases and in the scientific understanding thereof. Most interest in this group of parasites stems from the serious diseases that they cause in humans. It is through this lens that we summarize here the most important breakthroughs that have made a difference to the treatment of human diseases caused by these parasites, reduction in transmission of the taeniid species associated with human disease, or understanding of the parasites' biology likely to impact diagnosis or treatment in the foreseeable future.
View Article and Find Full Text PDFEpidemiological characteristics of hepatic echinococcosis, concurrent cerebral echinococcosis, and pulmonary echinococcosis in Ganzi County, Sichuan Province, China.
Medicine (Baltimore)
April 2020
Radiology, The First People's Hospital of Lognquanyi District, Chengdu, Sichuan, China.
Human echinococcosis has become a major public health problem in most parts of the world. The objective of this article was to study the demographics of patients with hepatic echinococcosis in Ganzi County to elucidate the main risk factors, as well as to report the concurrent prevalence of cerebral echinococcosis and pulmonary echinococcosis.We recruited 195 patients with hepatic echinococcosis from the Datongma area of Ganzi County from January 2018 to November 2018.
View Article and Find Full Text PDFRecent advancements and new perspectives in animal models for Neurocysticercosis immunopathogenesis.
Parasite Immunol
July 2017
School of Basic Sciences, Indian Institute of Technology Mandi, Mandi, India.
Neurocysticercosis (NCC), one of the most common parasitic diseases of the central nervous system, is caused by Taenia solium. This parasite involves two hosts, intermediate hosts (pig and human) and a definitive host (human) and has various stages in its complex life cycle (eggs, oncosphere, cysticerci and adult tapeworm). Hence, developing an animal model for T.
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