Umbilical vessel catheterization is a common procedure in Neonatal Intensive Care Units, especially in very low birthweight infants. Rarely, umbilical artery catheters break, and the retained fragments can cause thrombosis, infection, distal embolization, and even death. Herein, we describe a neonate with clinically significant bilateral limb ischemia developing after removal of a broken umbilical artery catheter. He was under vasodilator treatment in addition to fibrinolytic and anticoagulants. The evolution was favourable.
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http://dx.doi.org/10.5546/aap.2015.eng.e283 | DOI Listing |
Diagnostics (Basel)
January 2025
Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Umbilical artery thrombosis (UAT) masquerading as a single umbilical artery (SUA) is a rare but critical diagnostic challenge in prenatal care. We described a case of a 22-year-old primigravida with an uneventful obstetric history who presented with reduced fetal movements at 22 weeks of gestation. Ultrasound showed no gross fetal structural anomalies while umbilical artery Doppler flow imaging revealed an isolated SUA.
View Article and Find Full Text PDFPostgrad Med J
January 2025
Department of Obstetrics and Gynecology, Chung Shan Hospital, No. 11, Ln. 112, Sec. 4, Ren'ai Rd., Da'an Dist., Taipei City 10689, Taiwan.
Background: Our study aims to evaluate the umbilical vein (UV) hemodynamic change in the prenatal cohort of pregnancies diagnosed with abnormal placental cord insertion (aPCI).
Methods: From January 2022 to December 2022, the fetal umbilical cord insertion site was sonographically examined in singleton fetuses, and umbilical cord blood flow was calculated. The umbilical artery and UV Doppler flow indexes were assessed in cases of normal and abnormal cord insertion.
J Gynecol Obstet Hum Reprod
January 2025
Maternite´ Port-Royal, AP-HP, APHP, Centre-Universite´ de Paris, FHU PREMA, 123, Bd de Port-Royal, 75014 Paris, France.
Objective: To study perinatal outcomes for newborns with early, isolated, severe FGR, for whom initial active management was considered unreasonable or impossible at an obstetric-pediatric assessment and to identify the determinants associated with a course that made active management reasonable.
Material And Methods: This retrospective observational single-center study occurred in a level-3 university hospital maternity unit. It included all pregnancies with a singleton fetus presenting isolated FGR <3rd percentile at 23 weeks or more of gestation with an obstetric-pediatric assessment (OPA) initially unfavorable to active management.
Chem Biol Interact
January 2025
College of Chemistry and Materials, Jiangxi Normal University, Nanchang, 330022, China. Electronic address:
As a replacement of bisphenol A, bisphenol S (BPS) is commonly used in the wrappers and food containers of daily life. Epidemiological studies demonstrate a close link between BPS exposure and vascular diseases, where the biological activities of BPS remain scarcely known. Herein, the effects of BPS on endothelial function as well as the underlying mechanism were investigated in human umbilical vein endothelial cells (HUVECs) and mouse arteries.
View Article and Find Full Text PDFJ Vasc Surg Cases Innov Tech
February 2025
Department of Vascular Surgery, Sir Charles Gairdner Hospital, Perth, Australia.
A 2-day-old neonate was referred to the vascular surgery service owing to concerns of limb perfusion after entrapment of a microcatheter in the middle cerebral artery. The catheter was inserted via the umbilical artery to treat a vein of Galen arteriovenous malformation. This catheter inadvertently became entrapped owing to device failure, was cut at the insertion site, and left in situ for 3 months.
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