AI Article Synopsis
- This study evaluated a low concentration fluoride strip (1450 ppm) for preventing tooth decay and found it effective in reducing enamel demineralization.
- After treatment with the fluoride strip, a protective CaF2 layer formed on the enamel, demonstrating significant fluoride infiltration and enhanced dental mineralization.
- The fluoride strip can serve as a practical topical fluoride delivery method, showing promise for caries prevention in general use.
Article Abstract
There is no topically applicable low concentration fluoride delivery device available for caries prevention. This study was aimed to assess the use of a low concentration (1450 ppm) fluoride strip as an effective fluoride delivery system against enamel demineralization. The enamel surface composition and calcium-deficient hydroxyapatite or toothpaste treatments were investigated using X-ray photoelectron spectroscopy. In vitro enamel demineralization was assayed using a pH cycling model and the dissolution of calcium ions from the treated specimens was quantified using ion chromatography. After 24-hr fluoride-strip treatment, the enamel was covered with a CaF2 layer which showed a granular morphology of 1 μm in size. Below the CaF2 layer was a region of mixed fluorapatite and CaF2. Fluoride infiltrated extensively in enamel to produce highly fluorinated fluorohydroxyapatite. In comparison, low-fluoride-level fluorinated fluorohydroxyapatite was formed on the enamel specimen exposed to toothpaste. The treatments with the fluoride strip as short as 1 hr significantly inhibited enamel demineralization. The fluoride strip was effective for topical fluoride delivery and inhibited in vitro demineralization of enamel by forming CaF2 and fluoride-containing apatites at the enamel surface. It exhibited the potential as an effective fluoride delivery device for general use in prevention of caries.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543969 | PMC |
| http://dx.doi.org/10.1038/srep13352 | DOI Listing |
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