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Predictors and prognosis of elderly hip fracture patients with perioperative atrial fibrillation: a nested case-control study.
BMC Geriatr
January 2025
Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, No.139, ZiQiang Lu, Shijiazhuang, Hebei, 050051, PR China.
Background: A scarcity of data exists concerning atrial fibrillation (AF) during the perioperative stage of non-cardiothoracic surgery, particularly orthopedic surgery. In addition, given the frequency and significant impact of AF in the perioperative period, therefore our aim was to identify prognosis and predictors of elderly hip fracture patients with perioperative AF.
Methods: An examination of hip fracture patients at the Third Hospital of Hebei Medical University, who had been hospitalized from January 2018 to October 2020 in succession, was conducted retrospectively.
Drug-induced hyponatraemia and possible related signals: Analysis of 659 cases reported to the Spanish Pharmacovigilance System and disproportionality analysis.
Med Clin (Barc)
December 2024
Centre for Research on Drug Safety (CESME), Department of Cell Biology, Histology, Pharmacology and Genetics, Faculty of Medicine, University of Valladolid (Centro de Estudios Sobre la Seguridad de los Medicamentos (CESME), Departamento de Biología Celular, Histología, Farmacología y Genética, Facultad de Medicina, Universidad de Valladolid), Valladolid, Spain; Research Group Pharmacogenetics, Cancer Genetics, Genetic Polymorphisms and Pharmacoepidemiology, University of Valladolid (GIR Farmacogenética, Genética del Cáncer, Polimorfismos Genéticos y Farmacoepidemiología, Universidad de Valladolid), Spain. Electronic address:
Article Synopsis
- Hyponatraemia can adversely affect cognitive function and increase risks for falls, fractures, and even hospital mortality.
- The objective of the study was to identify safety signals related to drug-induced hyponatraemia and analyze cases reported in the Spanish Pharmacovigilance System.
- The analysis revealed 659 cases of suspected drug-induced hyponatraemia, with a significant increase over five years; most cases were serious, affecting primarily elderly women, and were commonly associated with diuretics and antidepressants.
Frequency and severity of hyponatremia in healthy children with acute illness.
Pediatr Nephrol
October 2024
Department of Nephrology and Rheumatology, Tokyo Metropolitan Children's Medical Center, 2-8-29 Musashidai, Fuchu, Tokyo, 183-8561, Japan.
Article Synopsis
- Hyponatremia is a condition marked by low sodium levels and can occur during the acute phase of many illnesses, but its prevalence and severity in various medical situations is not fully understood.
- A study at Tokyo Metropolitan Children's Medical Center reviewed 2,717 urgent pediatric admissions and found that 260 (13.8%) had hyponatremia, with type 1 diabetes being the most common associated condition (69%).
- The research highlighted significant hyponatremia in conditions like Kawasaki disease and acute infectious encephalopathy, but noted that conditions like acute bronchial asthma or fractures rarely showed low sodium levels upon arrival.
Acetabular Bone Cement Extension Leading to Bladder Obstruction: An Orthopedic Surgical Complication.
Cureus
September 2024
Department of Pathology, William Carey University College of Osteopathic Medicine, Hattiesburg, USA.
Article Synopsis
- - Polymethyl methacrylate, or bone cement, is commonly used in surgeries for its strong adhesive qualities but can sometimes lead to complications like extrusion, which poses health risks.
- - An 86-year-old woman with several health issues presented with severe symptoms and was found to have bone cement extruding into her bladder after hip surgery, causing hydronephrosis and a urinary tract infection.
- - This case emphasizes the need for awareness of potential complications from hip replacement surgeries, even if they are typically asymptomatic in some patients.
Adverse outcomes and mortality in individuals with eating disorder-related electrolyte abnormalities in Ontario, Canada: a population-based cohort study.
Lancet Psychiatry
October 2024
Ottawa Hospital Research Institute Clinical Epidemiology Program, University of Ottawa, Ottawa, ON, Canada; Department of Medicine, University of Ottawa, The Ottawa Hospital, Ottawa, ON, Canada.
Article Synopsis
- * A study in Ontario analyzed data from over 6,000 patients with eating disorders, revealing significant correlations between electrolyte issues and increased risks of hospitalization, cardiac events, and mortality.
- * The most common electrolyte abnormalities found were hypokalaemia and hyponatraemia, with those affected showing a higher mortality rate (15.7%) compared to those without such abnormalities (5.6%).
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