D-penicillamine interferes with elastin and collagen metabolism and produces several cutaneous and multi-systemic side-effects. We present two cases of Wilson's disease who on long-term penicillamine therapy developed drug-induced degenerative dermopathy manifesting as skin fragility over pressure sites and cutis laxa-like changes.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533546 | PMC |
| http://dx.doi.org/10.4103/0019-5154.160498 | DOI Listing |
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