253 cooking plant workers employed for 5 years were examined. 207 of them were exposed to very high concentrations of BaP and tar substances, as well as to benzene, its homologues and CO at concentrations not exceeding MAC values. In 20% of the examined workers of the baking ovens department exposed to very high BaP concentrations an abnormal activity of marker enzymes was demonstrated, while in 63% of workers C-14 aminopyrine test was pathologic. These facts indicate that hepatocyte microsomal injury may be affected by toxic effects of BaP. The stool occult blood test was positive in 4% of subjects, which resulted from some non-malignant diseases of the digestive system.
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